Back to Journals » Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy » Volume 10

Changes in muscle strength after diet-induced weight reduction in adult men with obesity: a prospective study

Authors Kim B, Tsujimoto T, So R, Zhao X, Oh S, Tanaka K

Received 20 January 2017

Accepted for publication 13 March 2017

Published 9 May 2017 Volume 2017:10 Pages 187—194

DOI https://doi.org/10.2147/DMSO.S132707

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Lucy Goodman

Peer reviewer comments 2

Editor who approved publication: Professor Ming-Hui Zou


Bokun Kim,1 Takehiko Tsujimoto,2,3 Rina So,4 Xiaoguang Zhao,5 Sechang Oh,6,7 Kiyoji Tanaka2

1Faculty of Sports Health Care, Inje University, Gyeongsangnamdo, Republic of Korea; 2Faculty of Health and Sport Sciences, University of Tsukuba, Ibaraki, 3Faculty of Human Sciences, Shimane University, Shimane, 4Research Center for Overwork-Related Disorders, National Institute of Occupational Safety and Health, Kawasaki, Kanagawa, 5Doctoral Program in Sports Medicine, Graduate School of Comprehensive Human Sciences, 6Faculty of Medicine, University of Tsukuba, 7The Center of Sports Medicine and Health Sciences, University of Tsukuba Hospital, Tsukuba, Ibaraki, Japan

Background and objective: The benefits of weight reduction for musculoskeletal disorders are well understood. Steep declines in muscle mass following considerable weight reduction can decrease muscle strength and, consequently, physical performance. However, only a limited number of studies have examined the changes in muscle mass and strength in the context of interventional weight reduction programs. Thus, we investigated the influence of muscle mass decrease caused by diet-induced weight reduction on muscle strength in obese men.
Methods: A total of 24 men with obesity (body mass index [BMI]: 29.2 ± 2.6 kg/m2; age: 52.4 ± 10.0 years) attended a 12-week weight reduction program that implemented dietary restrictions. Each participant underwent assessments of body weight (by a digital scale), body composition (by whole-body dual-energy X-ray absorptiometry [DEXA]), and upper and lower extremity muscle strength (by a hand-held dynamometer and a Biodex System 3 dynamometer, respectively) before and after the program.
Results: The program led to significant reductions of 10.5% of weight and 6.1% of lower extremity muscle mass. Similarly, lower extremity muscle strength (measured using a Biodex System 3 dynamometer) was significantly decreased (isometric 60° peak torque decreased by 10% and isokinetic 60°/s peak torque decreased by 9.4%); however, the level of body weight-normalized lower extremity muscle strength did not significantly change (increased by +1.2% and +1.4%). The decrease in muscle strength was related to but did not entirely depend on decrease in muscle mass. Although handgrip strength did not significantly differ (−2.2%), the weight-normalized level of this parameter significantly improved (+9.1%). In addition, decrease in the percentage of whole-body fat mass and increase in the percentage of muscle mass index were observed.
Conclusion: We recommend performing exercise after diet-induced weight reduction to regain muscle mass and strength and improve body weight-normalized lower extremity muscle strength.

Keywords: dietary restriction, muscle mass, muscle strength, obesity, weight reduction

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]