Back to Journals » Journal of Pain Research » Volume 11

Cerebral blood flow velocity in migraine and chronic tension-type headache patients

Authors Karacay Ozkalayci S, Nazliel B, Batur Caglayan HZ, Irkec C

Received 16 June 2017

Accepted for publication 9 August 2017

Published 4 April 2018 Volume 2018:11 Pages 661—666


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Katherine Hanlon

S Karacay Ozkalayci, B Nazliel, HZ Batur Caglayan, C Irkec

Department of Neurology, Faculty of Medicine, Gazi University, Ankara, Turkey

Introduction: The present study seeks to use transcranial Doppler ultrasound to evaluate cerebral blood flow velocities in anterior and posterior circulation arteries, during an attack-free episode in migraine patients, with and without aura, as well as in chronic tension-type headache patients who were not receiving prophylactic medication.
Methods: A total of 50 patients (35 female, 15 male) were evaluated during a headache-free episode: 30 migraine patients without aura (mean age: 32±8 years), 10 migraine patients with aura (mean age: 34±4 years), and 10 patients with chronic tension-type headache (mean age: 34±5 years).
Results: No significant difference was present between anterior, middle, and posterior cerebral and vertebral arteries’ blood flow velocities between migraine patients, with and without aura, or in patients with a tension-type headache, and normal controls (p>0.05). However, a significant increase in basilar artery cerebral blood flow velocities relative to controls was present in patients with a tension-type headache (p>0.001).
Conclusion: It is difficult to predict the main reason for the significant increase in basilar artery blood flow velocities in patients with chronic tension-type headache. It may be due to constriction of conductance or the dilatation of the resistance vessels.

Keywords: cerebral blood flow, migraine without aura, migraine with aura, tension-type headache, transcranial Doppler ultrasonography

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]