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Biochemical Parameters in Cognitive Functions

Authors Popiolek AK, Chyrek-Tomaszewska A, Stachowicz-Karpińska A, Bieliński MK, Borkowska A

Received 14 June 2020

Accepted for publication 8 September 2020

Published 27 October 2020 Volume 2020:16 Pages 2479—2489

DOI https://doi.org/10.2147/NDT.S267673

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Dr Roger Pinder


Alicja Katarzyna Popiołek,1,2 Aleksandra Chyrek-Tomaszewska,1,2 Agnieszka Stachowicz-Karpińska,1,2 Maciej Kazimierz Bieliński,1,2 Alina Borkowska1

1Department of Clinical Neuropsychology, Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland; 2Department of Vascular and Internal Diseases, Jan Biziel University Hospital No. 2 in Bydgoszcz, Bydgoszcz, Poland

Correspondence: Alicja Katarzyna Popiołek
Department of Clinical Neuropsychology, Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz, Skłodowskiej-Curie St. 75, Bydgoszcz 85-094, Poland
Tel/Fax +48 52 585 37 03
Email popiolek.ala@gmail.com

Abstract: Cognitive impairment is a common disease. Many studies attempt to explain the mechanisms of these dysfunctions formation, including correlations between cognitive functions and biochemical parameters. Scientists search for substances that would be indicators of cognitive functions and which could be determined in the cerebrospinal fluid or blood of the subjects. To date, they have isolated a few of such substances; however, research on their specificity, validity and the possibility of their use in diagnostics and prognostic assessment is still ongoing. However, there have been only few reports in the literature systematizing the existing knowledge on this subject, and they are mostly related to Alzheimer’s disease, not cognition in general, or referring only to a specific group of substances. This article discusses the most important biochemical exponents of cognitive functions.

Keywords: cognitive functions, biochemical markers, neuropsychology

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