Biobanking shifts to “precision medicine”
Aikaterini Ntai,1 Simona Baronchelli,2 Tatiana Pellegrino,1 Pasquale De Blasio,1 Ida Biunno2,3
1Integrated Systems Engineering, Milan, Italy; 2Institute for Genetic and Biomedical Research, National Research Council, Milan, Italy; 3IRCCS Multimedica, Milan, Italy
Abstract: The shape of the global health care system is changing rapidly to an approach that is much more patient-centered and focused on “precision medicine.” This is especially due to the development of large-scale “omics” biology results that rely on using and sharing sample collections and databases contained within bioresource facilities. “Personalized medicine” or “precision medicine” is the premise to help individuals to get the “right medicine for the right problem at the right time.” For several decades, tissues, body fluids, and cells obtained from patients with selected diseases have been cryopreserved in hospital-based biobanks, but samples were not accessible worldwide. Instead, the value of biobanks relies on the availability, at a necessary scale, of high-quality biospecimens and related data in order to respond to specific biological questions. However, the next generation of biobanks needs to face a major challenge – the costs related to the collection and processing of a large number of samples. Here, we describe the shift of biobanks from conventional repositories to functional infrastructures able to respond to specific medical demands.
Keywords: next-generation biobanking, personalized medicine, tumor biotypes
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