Other papers submitted by: Dr Perelman Sergio

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Paper published by Dr Perelman Sergio:

Original Research

Noteworthy Comment: This is an important and notable paper because it provides insight into possible methods for opposing age-related dementia and Alzheimer’s disease. It discusses how some retirement programs might impact cognitive functioning. The authors reviewed data from a large population of geographically distributed European individuals to determine if activity is related to cognition in the elderly. The data suggested that, as the pathological process of normal aging proceeds, neuronal “plasticity” allow individuals with occupationally-enhanced cognitive reserve to tolerate greater numbers of brain lesions without comparable loss of function. Apparently they benefit from reserve of alternative brain networks. Thus, the authors conclude that despite inevitable age-related changes in brain structure, all types of occupational activities have a positive effect on cognitive functioning. However, questions still remain as to which types of occupations and activities are most beneficial.

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Occupational activity and cognitive reserve: implications in terms of prevention of cognitive aging and Alzheimer’s disease

Adam S, Bonsang E, Grotz C, Perelman S

Clinical Interventions in Aging 2013, 8:377-390

Published Date: 11 April 2013