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Papers published by Dr Simon Jaag:


Original Research

SNAr Reactive Pyrazine Derivatives as p53-Y220C Cleft Binders with Diverse Binding Modes

Graphical Abstract of SNAr Reactive Pyrazine Derivatives as p53-Y220C Cleft Binders with Diverse Binding Modes

Klett T, Stahlecker J, Schwer M, Jaag SJ, Masberg B, Knappe C, Lämmerhofer M, Stehle T, Boeckler FM

Drug Design, Development and Therapy 2025, 19:4727-4753

Published Date: 3 June 2025

Original Research

Screening of Covalent Kinase Inhibitors Yields Hits for Cysteine Protease USP7 / HAUSP

Graphical Abstract of Screening of Covalent Kinase Inhibitors Yields Hits for Cysteine Protease USP7 / HAUSP

Ernst LN, Jaag SJ, Wydra VR, Masberg B, Knappe C, Gerstenecker S, Serafim RAM, Liang XJ, Seidler NJ, Lämmerhofer M, Gehringer M, Boeckler FM

Drug Design, Development and Therapy 2025, 19:2253-2284

Published Date: 25 March 2025

Original Research

Evaluation of a Covalent Library of Diverse Warheads (CovLib) Binding to JNK3, USP7, or p53

Graphical Abstract of Evaluation of a Covalent Library of Diverse Warheads (CovLib) Binding to JNK3, USP7, or p53

Klett T, Schwer M, Ernst LN, Engelhardt MU, Jaag SJ, Masberg B, Knappe C, Lämmerhofer M, Gehringer M, Boeckler FM

Drug Design, Development and Therapy 2024, 18:2653-2679

Published Date: 1 July 2024