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Assessing the relationship between obesity and asthma in adolescent patients: a review
Received 27 April 2012
Accepted for publication 20 November 2012
Published 18 February 2013 Volume 2013:4 Pages 39—49
DOI https://doi.org/10.2147/AHMT.S26707
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Kristie R Ross, Meeghan A Hart
Department of Pediatrics, Rainbow Babies and Children's Hospital and Case Western Reserve University School of Medicine, Cleveland, OH, USA
Abstract: The parallel rise in the prevalence of obesity and asthma over the last several decades has led to an extensive line of investigation into the relationship between these two conditions. This review will discuss evidence from laboratory-based studies, observational clinical studies, and clinical trials that suggests that obesity adversely influences asthma through multiple mechanisms. The effect of obesity on asthma during adolescence, including asthma incidence, the severity and control of existing asthma, lung function, and exacerbations, will be reviewed.
Keywords: children, airway reactivity
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