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An international randomized study of a home-based self-management program for severe COPD: the COMET

Authors Bourbeau J, Casan P, Tognella S, Haidl P, Texereau J, Kessler R

Received 25 February 2016

Accepted for publication 27 April 2016

Published 28 June 2016 Volume 2016:11(1) Pages 1447—1451


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Richard Russell

Jean Bourbeau,1 Pere Casan,2 Silvia Tognella,3 Peter Haidl,4 Joëlle B Texereau,5,6 Romain Kessler7

On behalf of the COMET investigators

1Respiratory Epidemiology and Clinical Research Unit, Research Institute of the McGill University Health Centre, McGill University, Montreal, QC, Canada; 2Hospital Universitario Central de Asturias, Facultad de Medicina, Oviedo, Spain; 3Lung Department, Ospedale Orlandi, Bussolengo VR, Italy; 4Krankenhaus Kloster Grafschaft, Schmallenberg, Germany; 5Air Liquide Healthcare, Medical Research and Development, Jouy-en-Josas, 6Assistance Publique-Hôpitaux de Paris, Service de Physiologie Clinique, Hôpital Cochin, Paris, 7Department of Pulmonary Medicine, Translational Medicine Federation of Strasbourg, University Hospital of Strasbourg, Strasbourg, France

Introduction: Most hospitalizations and costs related to COPD are due to exacerbations and insufficient disease management. The COPD patient Management European Trial (COMET) is investigating a home-based multicomponent COPD self-management program designed to reduce exacerbations and hospital admissions.
Design: Multicenter parallel randomized controlled, open-label superiority trial.
Setting: Thirty-three hospitals in four European countries.
Participants: A total of 345 patients with Global initiative for chronic Obstructive Lung Disease III/IV COPD.
Intervention: The program includes extensive patient coaching by health care professionals to improve self-management (eg, develop skills to better manage their disease), an e-health platform for reporting frequent health status updates, rapid intervention when necessary, and oxygen therapy monitoring. Comparator is the usual management as per the center’s routine practice.
Main outcome measures: Yearly number of hospital days for acute care, exacerbation number, quality of life, deaths, and costs.

Keywords: COPD, disease management, exacerbations, hospitalization, home care, clinical trial

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