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Adverse drug reaction suggests by a clinical vignette

Authors Finestone A

Published 12 July 2011 Volume 2011:6 Pages 199—200


Albert J Finestone
Temple University School of Medicine, Philadelphia, PA, USA

I had a three-lobe pneumonia and toxic encephalopathy in 2004. A lumbar puncture did not show meningitis. Magnetic resonance imaging showed a macroadenoma of the pituitary gland. Prolactin level was significantly elevated, making the diagnosis a functioning prolactinoma requiring treatment. Initially, I was treated with the dopamine
agonist cabergoline, which is also used in much larger doses to treat Parkinsonism. Recent reports have indicated heart valve damage in Parkinsonism patients treated with ergot-derived dopamine-receptor agonists.

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