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Acute pain management in children

Authors Verghese S, Hannallah RS

Published 15 July 2010 Volume 2010:3 Pages 105—123

DOI https://doi.org/10.2147/JPR.S4554

Review by Single anonymous peer review

Peer reviewer comments 3


Susan T Verghese, Raafat S Hannallah

The George Washington University Medical Center, Division of Anesthesiology, Children’s National Medical Center, Washington, DC, USA

Abstract: The greatest advance in pediatric pain medicine is the recognition that untreated pain is a significant cause of morbidity and even mortality after surgical trauma. Accurate assessment of pain in different age groups and the effective treatment of postoperative pain is constantly being refined; with newer drugs being used alone or in combination with other drugs continues to be explored. Several advances in developmental neurobiology and pharmacology, knowledge of new analgesics and newer applications of old analgesics in the last two decades have helped the pediatric anesthesiologist in managing pain in children more efficiently. The latter include administering opioids via the skin and nasal mucosa and their addition into the neuraxial local anesthetics. Systemic opioids, nonsteroidal anti-inflammatory agents and regional analgesics alone or combined with additives are currently used to provide effective postoperative analgesia. These modalities are best utilized when combined as a multimodal approach to treat acute pain in the perioperative setting. The development of receptor specific drugs that can produce pain relief without the untoward side effects of respiratory depression will hasten the recovery and discharge of children after surgery. This review focuses on the overview of acute pain management in children, with an emphasis on pharmacological and regional anesthesia in achieving this goal.

Keywords: pediatric pain treatment, pain medication in children, pediatric regional anesthesia, pca and pcea in children, epidural additives

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