Back to Journals » Clinical Ophthalmology » Volume 10

Vogt–Koyanagi–Harada syndrome – current perspectives

Authors Baltmr A, Lightman S, Tomkins-Netzer O

Received 5 June 2016

Accepted for publication 22 September 2016

Published 24 November 2016 Volume 2016:10 Pages 2345—2361


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 4

Editor who approved publication: Dr Scott Fraser

Abeir Baltmr,1 Sue Lightman,1,2 Oren Tomkins-Netzer1–3

1Uveitis Service, Moorfields Eye Hospital, London, UK; 2Department of Clinical Ophthalmology, UCL Institute of Ophthalmology, London, UK; 3Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel

Abstract: Vogt–Koyanagi–Harada syndrome is a cause of noninfectious panuveitis, leading to significant vision loss in many patients. It is an autoimmune disease occurring in genetically susceptible individuals and clinically presents as bilateral panuveitis with serous retinal detachments and hyperemic, swollen optic discs, which are associated with neurological and auditory manifestations. Early diagnosis and prompt and adequate treatment with immunosuppressive agents (corticosteroids and other immunosuppressive drugs) may halt disease progression and prevent recurrences and vision loss. This review summarizes the current knowledge on the variable clinical aspects of this disease, highlighting diagnostic and treatment strategies.

Keywords: multifocal choroiditis, serous retinal detachment, panuveitis, sunset glow fundus, starry sky, corticosteroid

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]