Back to Journals » Journal of Blood Medicine » Volume 1

Venous thromboembolism and pregnancy

Authors D’Uva M, Di Micco P, Strina I, De Placido G

Published 3 March 2010 Volume 2010:1 Pages 9—12

DOI https://doi.org/10.2147/JBM.S8747

Review by Single-blind

Peer reviewer comments 1


Maristella D’Uva1, Pierpaolo Di Micco2, Ida Strina1, Giuseppe De Placido

1Department of Obstetrics and Gynecology and Human Reproduction, “Federico II” University of Naples, Naples, Italy; 2Internal Medicine Division, Buonconsiglio Fatebenefratelli Hospital of Naples, Naples, Italy

Abstract: In recent decades, the association between a hypercoagulable state and its causes and adverse pregnancy outcome, in particular recurrent pregnancy loss (RPL) has been studied extensively. Although the first studies were focused only on the association between thrombophilia and RPL, subsequent studies underlined also a potential role of antithrombotic treatment to prevent vascular complication such as venous thromboembolism (VTE) during pregnancy. Thromboprophylaxis should be considered also for pregnant subjects carriers of molecular thrombophilia or that previously experienced VTE, in order to prevent VTE during pregnancy, while antithrombotic treatment for VTE should be performed during all pregnant periods.

Keywords: thrombophilia, venous thromboembolism, recurrent pregnancy loss, factor V Leiden

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]