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Trigeminal neuralgia: successful antiepileptic drug combination therapy in three refractory cases

Authors Prisco L, Ganau M, Bigotto F, Zornada F

Published 10 August 2011 Volume 2011:3 Pages 43—45

DOI https://doi.org/10.2147/DHPS.S22385

Review by Single-blind

Peer reviewer comments 3

Lara Prisco1, Mario Ganau2, Federica Bigotto1, Francesca Zornada1
1Department of Anaesthesiology, Intensive Care and Emergency Medicine, University Hospital of Cattinara, 2Graduate School of Nanotechnology, University of Trieste, Italy

Abstract: Antiepileptic drug combination therapy remains an empirical second-line treatment approach in trigeminal neuralgia, after treatment with one antiepileptic drug or other nonantiepileptic drugs have failed. The results in three patients followed in our clinic are not sufficient to draw definitive conclusions, but suggest the possibility of developing this type of therapeutic approach further.

Keywords: trigeminal neuralgia, antiepileptic drugs, combination therapy

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