The effect of posterior sub-Tenon’s capsule triamcinolone acetonide injection to that of pars plana vitrectomy for diabetic macular edema
Authors Nonomura S, Oshitari T, Arai M, Sato E, Takatsuna Y, Baba T, Yamamoto S
Received 28 December 2013
Accepted for publication 18 February 2014
Published 30 April 2014 Volume 2014:8 Pages 825—830
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Sakiko Nonomura, Toshiyuki Oshitari, Miyuki Arai, Eiju Sato, Yoko Takatsuna, Takayuki Baba, Shuichi Yamamoto
Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chiba, Japan
Purpose: To compare the effect of posterior sub-Tenon’s capsule triamcinolone acetonide (STTA) injection to that of pars plana vitrectomy (PPV) for diabetic macular edema (DME).
Patients and methods: The medical records of 50 patients (52 eyes) with DME were reviewed. Twenty-six eyes underwent STTA (20 mg) and the other 26 eyes underwent vitrectomy combined with cataract surgery. The central macular thickness (CMT), measured by optical coherence tomography, and best-corrected visual acuity (BCVA) were determined before and 1, 3, and 6 months after treatment.
Results: The differences in the BCVA and the CMT between the STTA group and the PPV group were not significant before or at any time after the treatment. In both the STTA and PPV groups, there were significant differences between the pre-treatment CMT and BCVA at any time after treatment.
Conclusion: We recommend STTA injection for the treatment of DME.
Keywords: diabetic macular edema, posterior sub-Tenon’s capsule triamcinolone acetonide injection, pars plana vitrectomy, central macular thickness