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Swept Source Optical Coherence Tomography Compared to Ultrasound and Biomicroscopy for Diagnosis of Posterior Vitreous Detachment

Authors Wang MD, Truong C, Mammo Z, Hussnain SA, Chen RWS

Received 17 December 2020

Accepted for publication 19 January 2021

Published 11 February 2021 Volume 2021:15 Pages 507—512

DOI https://doi.org/10.2147/OPTH.S297307

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Dr Scott Fraser


Marlene D Wang, Cecile Truong, Zaid Mammo, Syed Amal Hussnain, Royce WS Chen

Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, New York, NY, 10032, USA

Correspondence: Royce WS Chen
Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, 635 W 165th St, New York, NY, 10032, USA
Tel +1 212-342-4570
Email Rc2631@cumc.columbia.edu

Background: Biomicroscopy, B-scan ultrasound imaging, and SD-OCT are all modalities used to characterize a posterior vitreous detachment (PVD). Our objective is to assess the precision of the diagnosis of PVD by SS-OCT.
Methods: This prospective observational study examines ninety-five eyes of forty-nine patients with biomicroscopy, B-scan ultrasound, and SS-OCT for the presence or absence of a complete PVD. All SS-OCT images were reviewed by two retina specialists (RWSC, ZM). All three diagnostic methods were evaluated for agreement by Cohen’s kappa statistic.
Results: The inter-rater reliability between retina specialists reading the SS-OCT images was 97.9% (κ = 0.957). Agreement on PVD status between SS-OCT and biomicroscopy was 85.3% (κ = 0.711). Agreement between SS-OCT and B-scan ultrasound was 83.2% (κ = 0.667). Agreement between B-scan ultrasound and biomicroscopy was 87.4% (κ = 0.743).
Conclusion: For the diagnosis of complete PVD, SS-OCT allows for high accuracy and agreement between graders.

Keywords: optical coherence tomography, swept source, posterior vitreous detachment

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