Dr Palas Chanda

      

Dr Palas Chanda

Consulting Editor: Palas Kumar Chanda (PhD)

Postdoctoral fellow, Houston Methodist Research Institute, Houston,TX, USA

I obtained my MS and M.Tech degree in Biochemistry and Biotechnology respectively.My research career started as a doctoral candidate at Bose Institute, Kolkata, India. I got trained as molecular biologist in the field of transcriptional regulation of gene expression. I worked on molecular mechanisms of antibiotic resistance of human pathogen Staphylococcus aureus and developed fluorescence based biological assay system to screen antistaphylococcal as well as hazardous compounds in a high throughput manner. Next, I joined University of Calcutta as Research Associate, a position equivalent to a postdoctoral fellow, as molecular biologist to work on sheath blight disease of rice plant, the idea was to utilize transcriptional regulation of pathogenesis related proteins of rice plant and develop sheath blight resistant transgenic rice. After enjoying my two years of work over there, I moved to USA as postdoctoral fellow to work transcriptional regulation of methicillin resistance Staphylococcus aureus (MRSA). Later on, I started to work in the field of stem cell research as molecular biologist. I started with investigating the role of circadian genes in determination of mesenchymal cell commitment towards a particular lineage (adipocytes, muscles, osteocytes etc). Presently I am working on the role of innate immunity in epigenetic regulation of nuclear reprogramming; a process in which terminally differentiated somatic cells could be reprogrammed back into an embryonic stem cell (ESCs) like state through activation of innate immunity involving global epigenetic changes.