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Proliferative Anterior Optic Membranes in Hydrophobic Acrylic Intraocular Lenses

Authors Riaz KM, Williams BL, Safran SG, Gallardo MJ

Received 26 August 2020

Accepted for publication 29 September 2020

Published 22 October 2020 Volume 2020:14 Pages 3451—3455

DOI https://doi.org/10.2147/OPTH.S265397

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


Kamran M Riaz,1 Blake L Williams,2 Steven G Safran,3 Mark J Gallardo4

1Department of Ophthalmology, Dean McGee Eye Institute/University of Oklahoma, Oklahoma City, OK, USA; 2Department of Ophthalmology and Visual Science, University of Chicago Medical Center, Chicago, IL, USA; 3Private Practice, Lawrenceville, NJ, USA; 4Private Practice, El Paso, TX, USA

Correspondence: Kamran M Riaz
Dean McGee Eye Institute/University of Oklahoma, 608 Stanton L Young Boulevard, Suite 313, Oklahoma City, OK 73104, USA
Tel +1 4052711095
Fax +1 4052713680
Email Kamran-Riaz@dmei.org

Purpose: To describe the observed stages of development and management of proliferative anterior optic membranes (AOM) seen on a popularly implanted single-piece hydrophobic intraocular lens (IOL).
Methods: This is an observational series of patients with AOMs managed by three surgeons in different geographical areas in the USA.
Results: AOMs may clinically present in one of the four distinct stages. Most patients were visually asymptomatic, but those with decreased visual acuity (Stage 4) required Nd:YAG laser treatment to remove the AOM. These patients had improved visual acuity without recurrence of the AOM during the one-year follow-up period.
Conclusion: AOMs can present and progress in four distinct stages with variable visual significance. AOMs may be safely and effectively treated with Nd:Yag laser. Occurrence of the membrane may be related to many factors, including high fibronectin content of this IOL. Additional studies are needed to identify incidence, etiology, and best management strategies.

Keywords: anterior optic membrane, hydrophobic intraocular lens, fibronectin, YAG laser

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