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Paraneoplastic neuromyelitis optica spectrum disorder associated with breast cancer

Authors Yuan J, Jia Z, Qin W, Hu W

Received 18 January 2019

Accepted for publication 24 April 2019

Published 6 June 2019 Volume 2019:14 Pages 1039—1044


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Zhi-Ying Wu

Junliang Yuan, Zejin Jia, Wei Qin, Wenli Hu

Department of Neurology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, People’s Republic of China

Abstract: Neuromyelitis optica spectrum disorder (NMOSD) is a group of inflammatory disease involving the central nervous system. Although most commonly an idiopathic autoimmune condition, NMOSD may also occur as a paraneoplastic syndrome in rare instances. Herein, we report a rare case of a 60-year-old woman with paraneoplastic NMOSD associated with breast cancer. Our findings increase the recognition that NMOSD may present as a paraneoplastic neurological syndrome associated with breast cancer. Our case also raises awareness of an important complication of neurological complications of breast cancer. Early diagnosis of paraneoplastic NMOSD may be imperative for a better prognosis.

Keywords: neuromyelitis optica spectrum disorder, paraneoplastic syndrome, breast cancer

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