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Outcome After Selective Laser Trabeculoplasty for Glaucoma Treatment in a Thai Population

Authors Funarunart P, Treesit I

Received 6 January 2021

Accepted for publication 5 March 2021

Published 18 March 2021 Volume 2021:15 Pages 1193—1200

DOI https://doi.org/10.2147/OPTH.S300621

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Dr Scott Fraser


Panrapee Funarunart, Isaraporn Treesit

Department of Ophthalmology, Phramongkutklao Hospital, Phramongkutklao College of Medicine, Bangkok, 10400, Thailand

Correspondence: Isaraporn Treesit
Department of Ophthalmology, Phramongkutklao Hospital, Phramongkutklao College of Medicine, Bangkok, 10400, Thailand
Tel +668 9665 1949
Fax +662 354 9309
Email [email protected]

Purpose: The study aimed to evaluate the efficacy and predictive factors of success after selective laser trabeculoplasty (SLT) for treating various types of open-angle glaucoma in a Thai population.
Design: The study employed a retrospective cohort design.
Materials and Methods: The study retrospectively recruited Thai subjects diagnosed with open-angle glaucoma receiving first time selective laser trabeculoplasty. Primary open-angle glaucoma (POAG), ocular hypertension (OHT) and other types of open-angle glaucoma were included. Reduced intraocular pressure (IOP) of 20% or decreased number of antiglaucoma drugs usage after SLT was defined as success. Various parameters were analyzed for association with SLT success.
Results: Ninety-six eyes were recruited in the study. Mean pre- and postSLT IOP were 19.31± 3.59 and 15.04± 3.13 mmHg, respectively. IOP decreased significantly in all follow-up visits (p< 0.001). Overall, 59.4% met the treatment endpoint. More than 10% postSLT IOP elevation at 1 hour was the only covariate positively associated with SLT success in both univariate (odds ratio (OR) = 1.042, p = 0.037) and multivariate analyses (OR = 1.040, p = 0.046). Underlying hypertension and preSLT IOP were negatively associated with SLT success in both univariate (OR = 0.970, p = 0.026, OR = 0.955, p < 0.001) and multivariate analysis (OR = 0.970, p = 0.026, OR = 0.991, p < 0.001).
Conclusion: IOP significantly decreased as well as the number of antiglaucoma drugs needed after SLT. More than 10% postSLT IOP elevation at 1 hour was a positive predictor whereas systemic hypertension and preSLT IOP were negative predictors of SLT success.

Keywords: selective laser trabeculoplasty, outcome, success, factors, Thai

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