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Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes in an older adult mimicking cerebral infarction: a Chinese case report

Authors Fang GL, Zheng Y, Zhang YX

Received 6 September 2018

Accepted for publication 6 November 2018

Published 27 November 2018 Volume 2018:13 Pages 2421—2424

DOI https://doi.org/10.2147/CIA.S186636

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Amy Norman

Peer reviewer comments 2

Editor who approved publication: Dr Zhi-Ying Wu


Gao-Li Fang,1 Yang Zheng,2 Yin-Xi Zhang2

1Department of Neurology, Hangzhou Red Cross Hospital, Hangzhou, China; 2Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China

Abstract: Few cases of mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) with an onset older than 60 years have been reported. Herein, we report a 63-year-old Chinese female initially suspected of ischemic infarction but was ultimately diagnosed with MELAS. Therefore, even in the elderly, a diagnosis of MELAS should be considered when encountering patients with recurrent stroke-like episodes, cognitive dysfunction, and psychotic symptoms. In order to achieve the correct diagnosis and launch the appropriate management in time, a detailed medical history together with appropriate diagnostic laboratory investigations should therefore be collected.

Keywords: mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes, adult late onset, cerebral infarction

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