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Management strategies of enterovirus D68 outbreaks: current perspectives

Authors Milhano N, Borge KS, Bragstad K, Dudman SG

Received 12 December 2017

Accepted for publication 2 February 2018

Published 13 March 2018 Volume 2018:10 Pages 1—7

DOI https://doi.org/10.2147/VAAT.S140376

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Cristina Weinberg

Peer reviewer comments 2

Editor who approved publication: Professor Jonathan Dinman


Natacha Milhano, Kaja Sverdrup Borge, Karoline Bragstad, Susanne G Dudman

Domain for Environmental Health and Infectious Disease Control, Norwegian Institute of Public Health, Oslo, Norway

Abstract: Following its discovery in California in 1962, enterovirus D68 (EV-D68) was reported only sporadically around the world. In August 2014, a marked increase of EV-D68 cases in young children with severe respiratory infections was reported in the USA and Canada and later in Europe and Asia. Some of these cases were also found to be associated with acute flaccid paralysis, which exacerbated public health concern, and has since triggered international efforts to strengthen both EV-D68 and acute flaccid paralysis surveillance systems. This review summarizes the current knowledge on EV-D68, offering an overview of EV-D68 epidemiology, clinical presentations, diagnostic methodologies, and treatment strategies, as well as surveillance and outbreak management.

Keywords: enterovirus D68, AFP, diagnostics, treatment, surveillance, outbreak
 

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