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Light-chain cardiac amyloidosis with neuropathy: a case report

Authors Xu Z, Li Y, Liu L, Zhou B

Received 29 April 2015

Accepted for publication 15 June 2015

Published 31 July 2015 Volume 2015:10 Pages 1219—1222


Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Dr Wu

Zhan-Wen Xu,1 Ya-Qin Li,1 Li-xia Liu,2 Bing-Juan Zhou3

1Department of Cardiology, 2Department of Ultrasound, Affiliated Hospital of Hebei University, 3Department of Pathology, Baoding First Central Hospital, Baoding, People’s Republic of China

Abstract: Light-chain amyloidosis is a relatively rare multisystem disorder. The disease often is normally difficult to diagnose due to its broad range of characters without specific symptoms. A 62-year-old male patient presented with heart failure after experiencing a long period of unexplained and untreated gastrointestinal symptoms. Clinical examination and laboratory findings indicated a systemic process with cardiac involvement. Echocardiography revealed concentric left ventricular hypertrophy with enhanced echogenicity and preserved ejection fraction. Rectum biopsy confirmed amyloid deposition. The side effect of delayed diagnosis on prognosis and the appropriate diagnostic strategy has been discussed.

Keywords: light-chain amyloidosis, cardiac amyloidosis, echocardiography, autonomic neuropathy, peripheral neuropathy

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