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Optimal treatment of actinic keratosis

Authors Goldenberg G, Markowitz O

Received 13 September 2013

Accepted for publication 14 September 2013

Published 9 December 2013 Volume 2014:9 Pages 15—16


Checked for plagiarism Yes

Gary Goldenberg

Mount Sinai School of Medicine, New York, NY, USA

We read with interest the review by Uhlenhake on treatments for actinic keratosis (AK).1 The author presents a summary of the various AK treatment options used to reduce the risk of progression to invasive squamous cell carcinoma. The article includes a table (Table 1) comparing advantages and side effects of these options.
Patient-administered topical treatments are an important strategy for treating confluent AKs and areas of sun-damaged skin that may contain subclinical AKs. Rates of complete and partial clearance are similar across the topical agents (fluorouracil, imiquimod, diclofenac, and ingenol mebutate). It is noteworthy that the uniquely brief regimen for ingenol mebutate, 2 to 3 days, produced clearance rates similar to those with the other agents, which have treatment regimens of several weeks.1

View original paper by Uhlenhake.

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