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Intraocular pressure in patients with human immunodeficiency virus, correlation with TCD4, viral load and demographic characteristics: a case–control study

Authors Cravo LMS, Biancardi AL, Ronconi TB, Xavier VL, Moraes Jr H

Received 22 May 2019

Accepted for publication 18 June 2019

Published 5 August 2019 Volume 2019:13 Pages 1477—1483

DOI https://doi.org/10.2147/OPTH.S216759

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Nicola Ludin

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


Leonardo Medlig de Sousa Cravo,1 Ana Luiza Biancardi,2 Thamiles Batista Ronconi,3 Vinicius Layter Xavier,4 Haroldo Moraes Jr5

1Postgraduate Surgical Sciences, Hospital Universitário da Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21941-590, Brazil; 2Uveitis Ophthalmology Department, Hospital Universitário da Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21941-590, Brazil; 3Dermatology, Hospital Universitário da Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21941-590, Brazil; 4Statistics Department, Institute of Mathematics and Statistics, Universidade Estadual do Rio de Janeiro, Rio de Janeiro, RJ 20550-900, Brazil; 5Department of Ophthalmology, Hospital Universitário Da Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21941-590, Brazil

Purpose: To compare if patients with HIV have lower intraocular pressure than patients without HIV.
Methods: The association of intraocular pressure corrected by pachymetry and the relationship with viral load (VL) and TCD4 cells was studied. A total of 99 patients with HIV (91 who were on regular treatment and in control of the disease – group 1; and 8 who were without treatment – group 2) and 100 controls were studied.
Results: Only age was of statistical significance; the group with HIV without control of the disease was the youngest. There was a decrease of −1.54 mmHg in the IOP of group 1 in relation to the controls and −3.63 mmHg in the IOP of group 2 in relation to the controls.
Conclusion: HIV patients had lower IOP than the control population. However, the relationship between IOP, VL and TCD4 was not found.

Keywords: HIV, acquired immunodeficiency syndrome, intraocular pressure, ophthalmopathy

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