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Glucosamine hydrochloride for the treatment of osteoarthritis symptoms

Authors Fox B, Stephens MM

Published 15 January 2008 Volume 2007:2(4) Pages 599—604

DOI https://doi.org/10.2147/CIA.S1632


Beth Anne Fox, Mary M Stephens

East Tennessee State University, Family Physicians of Kingsport, Kingsport, TN, USA

Abstract: Osteoarthritis is the most common arthritis in the world. It affects millions of people with age being the greatest risk factor for developing the disease. The burden of disease will worsen with the aging of the world’s population. The disease causes pain and functional disability. The direct costs of osteoarthritis include hospital and physician visits, medications, and assistive services. The indirect costs include work absences and lost wages. Many studies have sought to find a therapy to relieve pain and reduce disability. Glucosamine hydrochloride (HCl) is one of these therapies. There are limited studies of glucosamine HCl in humans. Although some subjects do report statistically significant improvement in pain and function from products combining glucosamine HCl and other agents, glucosamine HCl by itself appears to offer little benefit to those suffering from osteoarthritis.
Keywords: osteoarthritis, glucosamine HCl, middle aged, aged, humans

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