Familial and Environmental Risk Predisposition in Tonsillectomy: A Case–Control Study
Received 18 April 2020
Accepted for publication 25 June 2020
Published 21 July 2020 Volume 2020:13 Pages 847—853
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Professor Marco Carotenuto
Majid Bani-Ata,1 Abdelwahab Aleshawi,2 Maulla Alali,1 Yazan Kanaan,1 Wala Al-Momani,1 Nadia Kanaan,2 Khalid Abdalla,3 Ala’’a Alhowary4
1Otolaryngology Department, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan; 2Intern, King Abdullah University Hospital, Jordan University of Science and Technology, Irbid 22110, Jordan; 3Radiology Department, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan; 4Anesthesia Department, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan
Correspondence: Majid Bani-Ata
Department of Special Surgery, Jordan University of Science and Technology, P.O. Box: 3030, Irbid 22110, Jordan
Background: Tonsillectomy is one of the most commonly performed procedures among children and it is the gold standard management to reduce episodes of tonsillitis and obstructive symptoms. Many studies showed a significantly higher incidence of previous tonsillectomy in the parents and siblings. This study investigated the influence of familial and environmental trends in tonsillectomy.
Methods: Retrospectively, we identified those patients who underwent tonsillectomy (the case group). Also, a control group of participants attending the hospital as visitors who had not undergone tonsillectomy was collected. Both groups are compared using the proper statistical tests.
Results: This study included 1,232 participants; 615 underwent tonsillectomy (cases) and 617 did not (controls). It was found that paternal and maternal history of tonsillectomy, childhood asthma, and daycare attendance are independent factors influencing tonsillectomy in the offspring. Of about 85.4% of fathers who underwent tonsillectomy their children will also have tonsillectomy. Also, regarding the maternal history, 72.5% of offspring will have tonsillectomy if the mothers underwent the procedure.
Conclusion: This study reveals that genetic predisposition factors may have a role for tonsillectomy and its underlying causative indications. Also, it highlights the importance of asthma control in children. Moreover, the role of ethnicity may be minimal due to the similar trend of this study with other studies. Further studies and prospective research are recommended.
Keywords: tonsillectomy, tonsillitis, family history, asthma
This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.Download Article [PDF] View Full Text [HTML][Machine readable]