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EX-PRESS Glaucoma Filtration Device: efficacy, safety, and predictability

Authors Chan J, Netland P

Received 16 June 2015

Accepted for publication 14 July 2015

Published 2 September 2015 Volume 2015:8 Pages 381—388

DOI https://doi.org/10.2147/MDER.S63350

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Dr Scott Fraser


Jessica E Chan, Peter A Netland

Department of Ophthalmology, University of Virginia School of Medicine, Charlottesville, VA, USA

Abstract: Trabeculectomy has been the traditional primary surgical therapy for open-angle glaucoma. While trabeculectomy is effective in lowering intraocular pressure, complications associated with the procedure have motivated the development of alternative techniques and devices, including the EX-PRESS Glaucoma Filtration Device. This review describes the efficacy, safety, complication rates, and potential advantages and disadvantages of the EX-PRESS Glaucoma Filtration Device. EX-PRESS implantation is technically simpler compared with that of trabeculectomy, with fewer surgical steps. Vision recovery has been more rapid after EX-PRESS implantation compared with trabeculectomy. Intraocular pressure variation is lower during the early postoperative period, indicating a more predictable procedure. While efficacy of the EX-PRESS implant has been comparable to trabeculectomy, postoperative complications appear less common after EX-PRESS implantation compared with trabeculectomy. The EX-PRESS Glaucoma Filtration Device appears to be safe and effective in the surgical management of open-angle glaucoma.

Keywords: surgery, trabeculectomy, mitomycin C, glaucoma drainage implant

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