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Emerging evidence on the link between depressive symptoms and bone loss in postmenopausal women

Authors Mollard E, Bilek L, Waltman N

Received 24 July 2017

Accepted for publication 17 November 2017

Published 28 December 2017 Volume 2018:10 Pages 1—9

DOI https://doi.org/10.2147/IJWH.S147006

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Amy Norman

Peer reviewer comments 4

Editor who approved publication: Professor Everett Magann


Elizabeth Mollard,1 Laura Bilek,2 Nancy Waltman1

1College of Nursing, University of Nebraska Medical Center, Lincoln, NE, 2College of Allied Health Professionals, University of Nebraska Medical Center, Omaha, NE, USA

Abstract: Osteoporosis and depression are major health problems of crisis proportions in postmenopausal women. Researchers have established a relationship between bone loss and depression, although few studies have focused on postmenopausal women. The purposes of this integrative review were to synthesize and summarize the available literature on: 1) the associations between bone loss and depression in postmenopausal women; and 2) potential variables that impact the associations between bone loss and depression in postmenopausal women. After searching the databases PubMed, CINAHL, Embase, and the Cochrane library between 2007 and 2017, 12 articles met the inclusion criteria. The majority of the included studies supported the relationship between depression and bone loss in postmenopausal women, although little information is offered as to why this relationship exists. This review summarizes the research that has been completed on depression and bone loss in postmenopausal women and identifies gaps in the literature. These findings will aid in the planning of future research and the development of health care recommendations.

Keywords: osteoporosis, depression, osteopenia, vitamin D, parathyroid, physical activity

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