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Drug-related problems in patients with erectile dysfunctions and multiple comorbidities

Authors Huri HZ, Ling CF, Razack AH

Received 24 July 2016

Accepted for publication 4 November 2016

Published 31 March 2017 Volume 2017:13 Pages 407—419

DOI https://doi.org/10.2147/TCRM.S118010

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Akshita Wason

Peer reviewer comments 2

Editor who approved publication: Professor Garry Walsh

Hasniza Zaman Huri,1,2 Chui Fang Ling,1 Azad Hassan Abdul Razack3

1Department of Pharmacy, Faculty of Medicine, University of Malaya, 2Clinical Investigation Centre, University Malaya Medical Centre, 3Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

Abstract: This study was conducted in a tertiary medical center in Kuala Lumpur, Malaysia. A total of 200 erectile dysfunction (ED) patients with 499 cases who had received pharmacological treatments for their ED participated in this study. Types, causes and factors associated with drug-related problems (DRPs) in ED patients with multiple comorbidities were assessed. A total of 244 DRPs with an average of 1.2±2.1 DRPs per patient were identified. Drug interaction contributed the most to DRPs occurrence. There was a significant higher risk of DRPs in patients with benign prostatic hyperplasia, lower urinary tract infection and elderly and end-stage renal disease. Early identification of types of DRPs and factors associated may enhance their prevention and management.

Keywords: ED drugs, DRPs, factors associated, prevention and management

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