Back to Journals » International Journal of Nanomedicine » Volume 10 » Issue 1

Docetaxel-loaded solid lipid nanoparticles as a basis for a targeted and dose-sparing personalized breast cancer treatment strategy

Authors Danilova NV, Kalzhanov ZR, Nefedova NA, Mal’kov PG, Kosmas IP, Eliseeva MY, Mynbaev OA

Received 7 November 2014

Accepted for publication 11 November 2014

Published 25 March 2015 Volume 2015:10(1) Pages 2417—2421

DOI https://doi.org/10.2147/IJN.S77186

Checked for plagiarism Yes

Editor who approved publication: Dr Thomas J Webster

Natalia V Danilova,1,2 Zhomart R Kalzhanov,3 Nina A Nefedova,2 Pavel G Mal’kov,2 Ioannis P Kosmas,1,4 Marina Y Eliseeva,1,5 Ospan A Mynbaev1,5,6

1International Translational Medicine and Biomodeling Research Team, MIPT Center for Human Physiology, Laboratory of Cellular and Molecular Technologies, Moscow Institute of Physics and Technology, State University, 2Department of Physiology and Basic Pathology, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Moscow, Russia; 3Department of Human Metabolism, Academic Unit of Reproductive and Developmental Medicine, Sheffield University, Sheffield, UK; 4Department of Obstetrics and Gynecology, Ioannina State General Hospital G Chatzikosta, Ioannina, Greece; 5Department of Obstetrics, Gynecology and Reproductive Medicine, Peoples’ Friendship University of Russia, 6Laboratory of Immunology, Moscow State University of Medicine and Dentistry named after AI Evdokimov, Moscow, Russia
 
The long-term survival rate of patients with breast cancer was improved by the application of systemic adjuvant chemotherapy,1 although the primary breast cancer treatment strategy consists of mastectomy with lymphadenectomy and radiotherapy followed by breast reconstruction.2–5 Unfortunately, most adjuvant chemotherapeutic agents trigger major side effects.1,6 Therefore, we have read with great interest an article in the International Journal of Nanomedicine on the design of docetaxel-loaded solid lipid nanoparticles (DSNs) aimed at reducing the systemic toxicity of standardized docetaxel treatment.7
 
Read the original article 

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]

 

Other articles by this author:

Inhibition of oxygen scavengers realized by peritoneal macrophages: an adhesion prevention target?

Mynbaev OA, Eliseeva MY, Kadayifci OT, Benhidjeb T, Stark M

International Journal of Nanomedicine 2014, 9:5259-5260

Published Date: 14 November 2014

Challenging nanoparticles: a target of personalized adhesion prevention strategy

Mynbaev OA, Eliseeva MY, Malvasi A, Tinelli A

International Journal of Nanomedicine 2014, 9:3375-3376

Published Date: 15 July 2014

Readers of this article also read:

Phthalocyanine-loaded graphene nanoplatform for imaging-guided combinatorial phototherapy

Taratula O, Patel M, Schumann C, Naleway MA, Pang AJ, He H, Taratula O

International Journal of Nanomedicine 2015, 10:2347-2362

Published Date: 24 March 2015

Electrospun gelatin/polycaprolactone nanofibrous membranes combined with a coculture of bone marrow stromal cells and chondrocytes for cartilage engineering

He X, Feng B, Huang C, Wang H, Ge Y, Hu R, Yin M, Xu Z, Wang W, Fu W, Zheng J

International Journal of Nanomedicine 2015, 10:2089-2099

Published Date: 17 March 2015

Folate-modified lipid–polymer hybrid nanoparticles for targeted paclitaxel delivery

Zhang L, Zhu D, Dong X, Sun H, Song C, Wang C, Kong D

International Journal of Nanomedicine 2015, 10:2101-2114

Published Date: 16 March 2015

Determination of factors controlling the particle size and entrapment efficiency of noscapine in PEG/PLA nanoparticles using artificial neural networks

Shalaby KS, Soliman ME, Casettari L, Bonacucina G, Cespi M, Palmieri GF, Sammour OA, El Shamy AA

International Journal of Nanomedicine 2014, 9:4953-4964

Published Date: 23 October 2014

The influence of bile salt on the chemotherapeutic response of docetaxel-loaded thermosensitive nanomicelles

Kim DW, Ramasamy T, Choi JY, Kim JH, Yong CS, Kim JO, Choi HG

International Journal of Nanomedicine 2014, 9:3815-3824

Published Date: 8 August 2014

Development and characterization of magnetic iron oxide nanoparticles with a cisplatin-bearing polymer coating for targeted drug delivery

Unterweger H, Tietze R, Janko C, Zaloga J, Lyer S, Dürr S, Taccardi N, Goudouri OM, Hoppe A, Eberbeck D, Schubert DW, Boccaccini AR, Alexiou C

International Journal of Nanomedicine 2014, 9:3659-3676

Published Date: 5 August 2014

Enhanced oral absorption and therapeutic effect of acetylpuerarin based on D-α-tocopheryl polyethylene glycol 1000 succinate nanoemulsions

Sun DQ, Wei XB, Xue X, Fang ZJ, Ren MR, Lou HY, Zhang XM

International Journal of Nanomedicine 2014, 9:3413-3423

Published Date: 18 July 2014