Back to Journals » International Journal of Women's Health » Volume 5

Crohn’s disease in women

Authors Plavšić I, Štimac T, Hauser G

Received 12 July 2013

Accepted for publication 11 September 2013

Published 18 October 2013 Volume 2013:5 Pages 681—688

DOI https://doi.org/10.2147/IJWH.S38083

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3


Ivana Plavšic,1 Tea Štimac,2 Goran Hauser3

1Health Center, County of Primorje-Gorski Kotar, Rijeka, Croatia; 2Department of Gynecology, 3Department of Gastroenterology, Clinical Hospital Center Rijeka, Rijeka, Croatia


Abstract: This article provides an overview of the obstetric and gynecological manifestations of Crohn’s disease (CD). High incidence of the new onset of the disease in young women in their reproductive years demands special concern from physicians involved in their treatment. Pregnant women with CD are considered high-risk patients, regardless of disease activity index, due to associated complications. Predominately described complications are premature birth, low birth weight, and congenital anomalies. To minimize the risk for adverse pregnancy/birth outcomes, it is recommended that remission be achieved before conception. Treatment of CD in pregnant women is similar to that among the nonpregnant population, and there is no valid reason to terminate it, since most of the drugs are proven to be safe. Women with CD who wish to conceive or are already pregnant need to be properly advised according to the newest guidelines on the subject, given by the European Crohn’s and Colitis Organization. Gynecological manifestations are another special feature of CD. They are important in that they may facilitate early recognition of the underlying disease, which usually stays unrecognized for years before intestinal manifestation; in this way, the underlying manifestations are often mistreated.

Keywords: adverse pregnancy outcome, Crohn’s disease, gynecological complications, immunosuppressive therapy

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]