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Copeptin in heart failure

Authors Lasota B, Mizia-Stec K

Received 11 November 2013

Accepted for publication 6 January 2014

Published 1 July 2014 Volume 2014:5 Pages 133—144

DOI https://doi.org/10.2147/RRCC.S43427

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4

Bartosz Lasota,1 Katarzyna Mizia-Stec2

12nd Department of Cardiology, Medical University of Silesia, Katowice, Poland; 21st Department of Cardiology, Medical University of Silesia, Katowice, Poland

Abstract: Copeptin is a novel indicator of arginine–vasopressin activation in the body. Its value has primarily been documented in acute life-threatening conditions mediated by the stress response system. Recently, some studies have revealed copeptin's promising role as a marker in cardiovascular diseases. In our review, we summarize the current knowledge on copeptin in pathophysiology, as well as in risk assessment in different clinical settings involving the cardiovascular system with a special focus on heart failure.

Keywords: copeptin, heart failure, arginine–vasopressin

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