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Chrysopogon zizanioides aqueous extract mediated synthesis characterization of crystalline silver and gold nanoparticles for biomedical applications

Authors Arunachalam KD, Annamalai SK

Received 15 February 2013

Accepted for publication 22 March 2013

Published 3 July 2013 Volume 2013:8(1) Pages 2375—2384

DOI https://doi.org/10.2147/IJN.S44076

Checked for plagiarism Yes

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Peer reviewer comments 3


Kantha D Arunachalam, Sathesh Kumar Annamalai

Center for Environmental Nuclear Research, Directorate of Research, SRM University, Chennai, Tamil Nadu, India

Abstract: The exploitation of various plant materials for the biosynthesis of nanoparticles is considered a green technology as it does not involve any harmful chemicals. The aim of this study was to develop a simple biological method for the synthesis of silver and gold nanoparticles using Chrysopogon zizanioides. To exploit various plant materials for the biosynthesis of nanoparticles was considered a green technology. An aqueous leaf extract of C. zizanioides was used to synthesize silver and gold nanoparticles by the bioreduction of silver nitrate (AgNO3) and chloroauric acid (HAuCl4) respectively. Water-soluble organics present in the plant materials were mainly responsible for reducing silver or gold ions to nanosized Ag or Au particles. The synthesized silver and gold nanoparticles were characterized by ultraviolet (UV)-visible spectroscopy, scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDAX), Fourier transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD) analysis. The kinetics decline reactions of aqueous silver/gold ion with the C. zizanioides crude extract were determined by UV-visible spectroscopy. SEM analysis showed that aqueous gold ions, when exposed to the extract were reduced and resulted in the biosynthesis of gold nanoparticles in the size range 20–50 nm. This eco-friendly approach for the synthesis of nanoparticles is simple, can be scaled up for large-scale production with powerful bioactivity as demonstrated by the synthesized silver nanoparticles. The synthesized nanoparticles can have clinical use as antibacterial, antioxidant, as well as cytotoxic agents and can be used for biomedical applications.

Keywords: nanoparticles, bioreduction, SEM, silver, gold

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