Chronic postcataract endophthalmitis caused by Penicillium species in an immunocompetent patient
Authors Kanda K, Takayama K, Enoki T, Takeuchi M
Received 25 May 2018
Accepted for publication 28 August 2018
Published 8 October 2018 Volume 2018:11 Pages 259—262
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Justinn Cochran
Peer reviewer comments 4
Editor who approved publication: Dr Scott Fraser
Koji Kanda,1 Kei Takayama,1 Toshio Enoki,2 Masaru Takeuchi1
1Department of Ophthalmology, National Defense Medical College, Tokorozawa, Japan; 2Enoki Eye Clinic, Sayama, Japan
Objective: Penicillium species are abundant, generally saprophytic, and widely distributed in the environment. On rare occasions, they cause endophthalmitis in immunocompromised patients or in immunocompetent patients with uncontrolled diabetic mellitus or immunosuppressive agents. We report a case of endophthalmitis caused by Penicillium species in an immunocompetent patient without any disorders.
Case presentation: A 67-year-old woman presented with ocular pain, hyperemia, and blurred vision in her right eye. She was in an immunocompetent condition and had received cataract surgery without complications 3 months ago. Severe cell infiltration and a clump of 3 mm diameter were found in the anterior chamber of the right eye, and there was no abnormality in the posterior segment. Serum β-d-glucan was not elevated; bacterial culture, histological analysis, and PCR using aqueous humor did not detect any pathogen (28S rDNA 2.4×102 copies/mL). However, because the clinical findings suggested fungal endophthalmitis, antifungal medication was initiated. The inflammation was gradually resolved with contraction of the clump; however, it recurred 47 days after the initiation by discontinuation of antifungal medication. Examination of culture identified Penicillium species in samples from both the anterior chamber and the vitreous.
Conclusion: Chronic postoperative endophthalmitis by Penicillium species can occur in an immunocompetent patient without any systemic diseases.
Keywords: endophthalmitis, immunocompetent, Penicillium, postcataract
This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.Download Article [PDF] View Full Text [HTML][Machine readable]