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Changing indications and techniques for corneal transplantations at a tertiary referral center in Turkey, from 1995 to 2014

Authors Altay Y, Burcu A, Aksoy G, Singar Ozdemir E, Ornek F

Received 11 December 2015

Accepted for publication 19 January 2016

Published 1 June 2016 Volume 2016:10 Pages 1007—1013

DOI https://doi.org/10.2147/OPTH.S102315

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Lucy Goodman

Peer reviewer comments 3

Editor who approved publication: Dr Scott Fraser


Yesim Altay, Ayse Burcu, Gozde Aksoy, Evin Singar Ozdemir, Firdevs Ornek

Department of Ophthalmology, Ankara Training and Research Hospital, Ankara, Turkey

Background: Indications for corneal transplantation in developed and developing nations differ according to the different spectrum of corneal disease in each country.
Objective: The purpose of this study is to analyze the changing indications and surgical techniques for corneal transplantation over the past 20 years at a tertiary referral center in Turkey.
Methods: We retrospectively reviewed the records of patients who underwent keratoplasty from January 1995 to December 2014 (between 1995 and 2004, period 1, and between 2005 and 2014, period 2). Patients’ demographic data, indications for corneal transplantation, and the type of surgery were recorded.
Results:
The number of keratoplasties performed ranged from 548 in period 1 to 782 in period 2. Between 1995 and 2004, the leading indications were keratoconus (34.1%), bullous keratopathy (17%), and non-herpetic corneal scar (13.3%), and between 2005 and 2014, they were keratoconus (33.8%), corneal stromal dystrophy (14.2%), and bullous keratopathy (12.7%). All the keratoplasties performed in the 1995–2004 period were penetrating keratoplasty (PKP). During the period 2005–2014, PKP accounted for 93%, automated lamellar keratoplasty 5.8%, and deep anterior lamellar keratoplasty 1.2% of all corneal transplantations.
Conclusion:
Keratoconus was the leading indication for keratoplasty in both periods. In the 2005–2014 period, corneal stromal dystrophy increased significantly. All the keratoplasties performed in period 1 and 93% of all keratoplasties performed in period 2 were PKP.

Keywords:
corneal transplantation, indication, keratoconus, keratoplasty technique, pene­trating keratoplasty

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