Back to Journals » Therapeutics and Clinical Risk Management » Volume 4 » Issue 5

Beclomethasone/formoterol fixed combination for the management of asthma: patient considerations

Authors Nicolini G, Scichilone N, Bizzi A, Papi A, Fabbri LM

Published 10 October 2008 Volume 2008:4(5) Pages 855—864


Review by Single-blind

Peer reviewer comments 1

Gabriele Nicolini1, Nicola Scichilone2, Andrea Bizzi3, Alberto Papi4, Leonardo M Fabbri5

1Medical Department, Chiesi Farmaceutici, Parma, Italy; 2University of Palermo, DIMPEFINU, Palermo, Italy; 3Department of Scientific Affairs, Chiesi Farmaceutici, Parma, Italy; 4Research Center on Asthma and COPD, University of Ferrara, Ferrara, Italy; 5Section of Respiratory Diseases, University of Modena, Modena, Italy

Abstract: Drugs for asthma and other chronic obstructive diseases of the lungs should be preferably delivered by the inhalation route to match therapeutic effects with low systemic exposure. Inhaled drugs are delivered to the lungs via different devices, mainly metered dose inhalers and dry powder inhalers, each characterized by specific inhaler technique and instructions for use. The patient–device interaction is part of the prescribed therapy and can have a relevant impact on adherence and clinical outcomes. The most suitable device should be considered for each patient to assure the correct drug intake and adherence to the prescribed therapy. The development of new drugs/devices in the past decades improved the compliance with inhaler and possibly drug delivery to the bronchi. The present review focuses on the recently developed beclomethasone/formoterol extrafine fixed combination and technical aspects of drug delivery to the lungs in patient’s perspective.

Keywords: beclomethasone, formoterol, modulite, extrafine

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF] 


Readers of this article also read:

Identification of risk factors for hepatitis B and C in Peshawar, Pakistan

Shafiq M, Nadeem M, Sattar Z, Khan SM, Faheem SM, Ahsan I, Naheed R, Khattak TM, Akbar S, Khan MT, Khan MI, Khan MZ

HIV/AIDS - Research and Palliative Care 2015, 7:223-231

Published Date: 17 August 2015

Efficacy and tolerability of low-dose oral prolonged-release oxycodone/naloxone for chronic nononcological pain in older patients

Guerriero F, Sgarlata C, Marcassa C, Ricevuti G, Rollone M

Clinical Interventions in Aging 2015, 10:1-11

Published Date: 16 December 2014

Quantification of functional abilities in Rett syndrome: a comparison between stages III and IV

Monteiro CBM, Savelsbergh GJP, Smorenburg ARP, Graciani Z, Torriani-Pasin C, de Abreu LC, Valenti VE, Kok F

Neuropsychiatric Disease and Treatment 2014, 10:1213-1222

Published Date: 3 July 2014

Optimal management of shoulder impingement syndrome

Escamilla RF, Hooks TR, Wilk KE

Open Access Journal of Sports Medicine 2014, 5:13-24

Published Date: 28 February 2014

Portable microfluidic chip for detection of Escherichia coli in produce and blood

Wang S, Inci F, Chaunzwa TL, Ramanujam A, Vasudevan A, Subramanian S, Ip AC, Sridharan B, Gurkan UA, Demirci U

International Journal of Nanomedicine 2012, 7:2591-2600

Published Date: 29 May 2012

The cognitive effects and decrements following concussion

Tracey Covassin, Robert J Elbin

Open Access Journal of Sports Medicine 2010, 1:55-61

Published Date: 12 May 2010

Treatment of severe psoriasis with infliximab

JA Leman, AD Burden

Therapeutics and Clinical Risk Management 2008, 4:1165-1175

Published Date: 5 December 2008

Early discharge care with ongoing follow-up support may reduce hospital readmissions in COPD

Maria Lawlor, Sinead Kealy, Michelle Agnew, Bettina Korn, Jennifer Quinn, et al

International Journal of Chronic Obstructive Pulmonary Disease 2009, 4:55-60

Published Date: 30 October 2008

Assessment of COPD-related outcomes via a national electronic medical record database

Carl Asche, Qayyim Said, Vijay Joish, Charles Oaxaca Hall, Diana Brixner

International Journal of Chronic Obstructive Pulmonary Disease 2008, 3:323-326

Published Date: 6 June 2008