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Available Evidence and Ongoing Hypothesis on Corona Virus (COVID-19) and Psychosis: Is Corona Virus and Psychosis Related? A Narrative Review

Authors Tariku M, Hajure M

Received 27 May 2020

Accepted for publication 6 August 2020

Published 18 August 2020 Volume 2020:13 Pages 701—704

DOI https://doi.org/10.2147/PRBM.S264235

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 4

Editor who approved publication: Professor Igor Elman


Mandaras Tariku,1 Mohammedamin Hajure2

1Department of Psychiatry, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia; 2Department of Psychiatry, College of Health and Medical Sciences, Mettu University, Mettu, Ethiopia

Correspondence: Mandaras Tariku Email [email protected]

Background: Corona virus (COVID-19) is an outbreak of respiratory disease caused by a novel corona virus and declared to be a global health emergency and a pandemic by the World Health Organization (WHO) on March 11, 2020. Prevention strategies to control the transmission of the COVID-19 pandemic, such as closing of schools, refraining from gathering, and social distancing, have direct impacts on mental well-being. SARS-CoV-2 has a devastating psychological impact on the mental health status of the community and, particularly when associated with psychotic symptoms, it could affect the overall quality-of-life. The virus also has the potential to enter and infect the brain. As a result, psychosis symptoms could be an emerging phenomenon associated with the corona virus pandemic. The presence of psychotic symptoms may complicate the management options of patients with COVID-19.
Objective: The aim of this article review is to elaborate the relationships between COVID-19 and psychotic symptoms.
Methodology: We independently searched different electronic databases, such as Google scholar, PubMed, Medline, CINAHL, EMBASE, PsychInfo, and other relevant sources published in English globally, by using the search terms “psychosis and COVID-19”, “corona virus”, “brief psychotic”, “schizophrenia”, “organic psychosis”, “infectious disease”, “mental illness”, “pandemics”, and “psychiatry” in various permutations and combinations.
Results: The results of the included studies revealed that patients with a novel corona virus had psychotic symptoms, including hallucination in different forms of modality, delusion, disorganized speech, and grossly disorganized or catatonic behaviors. The patients with COVID-19-related psychotic symptoms had responded with a short-term administration of the antipsychotic medication.
Conclusion and Recommendation: A corona virus-related psychosis has been identified in different nations, but it is difficult to conclude that a novel corona virus has been biologically related to psychosis or exacerbates psychotic symptoms. Therefore, to identify the causal relationships between COVID-19 and psychosis, the researchers should investigate the prospective study on the direct biological impacts of COVID-19 and psychosis, and the clinicians should pay attention for psychotic symptoms at the treatment center and isolation rooms in order to reduce the complication of a novel corona virus.

Keywords: COVID-19, psychosis, SARS-CoV-2, 2020

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