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An evaluation of prefilled insulin pens: a focus on the Next Generation FlexPen®

Authors Davis E, Sexson EL, Spangler ML, Foral PA

Published 26 August 2010 Volume 2010:3 Pages 41—50

DOI https://doi.org/10.2147/MDER.S11730

Review by Single-blind

Peer reviewer comments 2


Estella M Davis, Emily L Sexson, Mikayla L Spangler, Pamela A Foral
Department of Pharmacy Practice, Creighton University School of Pharmacy and Health Professions, Omaha, Nebraska, USA
Abstract: Insulin pen delivery systems are preferred by patients over the traditional vial and syringe method for insulin delivery because they are simple and easy to use, improve confidence in dosing insulin, and have less interference with activities and improved discretion with use. Insulin manufacturers have made numerous improvements to their first marketed pen devices and are now introducing their next generation of devices. Design modifications to the newest generation of prefilled insulin pen devices are intended to improve the ease of use and safety and continue to positively impact adherence to insulin. This review focuses on the Next Generation FlexPen® with regard to design considerations to reduce injection force, improve accuracy and ease of use, and evaluate the preference of patient and health-care provider compared with other disposable, prefilled insulin pen devices.
Keywords: diabetes, dose accuracy, injection force, patient preference, insulin pen device

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