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Acotiamide hydrochloride hydrate added to combination treatment with an α-blocker and a cholinergic drug improved the QOL of women with acute urinary retention: case series

Authors Sugimoto K, Akiyama T, Shimizu N, Matsumura N, Hashimoto M, Minami T, Nose K, Nozawa M, Yoshimura K, Uemura H

Received 4 February 2017

Accepted for publication 7 July 2017

Published 11 August 2017 Volume 2017:9 Pages 141—143

DOI https://doi.org/10.2147/RRU.S133952

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Akshita Wason

Peer reviewer comments 4

Editor who approved publication: Dr Jan Colli


Koichi Sugimoto,1,2 Takahiro Akiyama,2 Nobutaka Shimizu,1 Naoki Matsumura,1,2 Mamoru Hashimoto,1 Takafumi Minami,1 Kazuhiro Nose,1 Masahiro Nozawa,1 Kazuhiro Yoshimura,1 Hirotsugu Uemura1

1Department of Urology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan; 2Department of Urology, Sakai-Onshinkai Hospital, Sakai, Osaka, Japan

Abstract: Acute urinary retention is the most common urological emergency. To resolve this emergency, urethral catheterization is performed. If the procedure fails and permanent transurethral catheterization is required, the patient’s quality of life is significantly affected. Therefore, catheter-free treatment is the ideal goal of therapy for patients with acute urinary retention. Especially, for women, placement of a catheter poses a cosmetic problem. Therefore, the aim of this study was to treat female patients who had already received urapidil/distigmine bromide with acotiamide. Acotiamide was administered at a dose of 100 mg three times daily for 2 weeks, and the outcome of trial without catheter was evaluated. Only female patients were enrolled for this study. Treatment proved successful and all patients become catheter free.

Keywords: female, acute urinary retention, acotiamide hydrochloride hydrate

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