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A Prospective Comparison of Wavefront-Guided LASIK versus Wavefront-Guided PRK After Previous Keratorefractive Surgery

Authors Lee MD, Chen LY, Tran EM, Manche EE

Received 11 August 2020

Accepted for publication 18 September 2020

Published 20 October 2020 Volume 2020:14 Pages 3411—3419

DOI https://doi.org/10.2147/OPTH.S276381

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Dr Scott Fraser


Michele D Lee,1 Lisa Y Chen,2 Elaine M Tran,2 Edward E Manche2

1Department of Ophthalmology, University of Washington, Seattle, WA, USA; 2Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA

Correspondence: Edward E Manche
Byers Eye Institute, Stanford University School of Medicine, 2452 Watson Court, Palo Alto, CA 94303, USA
Tel +1 650-723-6995
Fax +1 650-498-6488
Email Edward.Manche@stanford.edu

Purpose: To compare the results of retreatment with wavefront-guided LASIK versus wavefront-guided PRK for residual refractive error following previous myopic keratorefractive surgery.
Methods: In this prospective study, 32 eyes of 28 patients after prior myopic keratorefractive surgery underwent retreatment with flap-lift wavefront-guided LASIK (n = 12) or wavefront-guided PRK (n = 20) for residual refractive error. Safety, efficacy, predictability, and wavefront outcomes were evaluated.
Results: At last follow-up, both LASIK and PRK retreatment resulted in similar improvement in visual acuity with respective mean ± standard deviation (SD) uncorrected distance visual acuity of − 0.07 ± 0.11 logMAR and − 0.06 ± 0.13 logMAR (p = 0.87). In the study, 16.7% of LASIK and 33.3% of PRK eyes gained one or more lines of best-corrected distance visual acuity (CDVA), while 16.7% and 9.5% of eyes lost one or more lines of CDVA with LASIK and PRK, respectively. One hundred % of LASIK eyes and 89.5% of PRK eyes were within ± 0.50 diopters of emmetropia. Wavefront analysis demonstrated similar reductions in total RMS error higher-order aberrations (p = 0.84) with no difference in coma, trefoil, or spherical aberration between eyes undergoing LASIK or PRK retreatment.
Conclusion: Wavefront-guided LASIK and wavefront-guided PRK following previous keratorefractive surgery demonstrate similar safety, efficacy, and predictability with comparable wavefront outcomes.

Keywords: LASIK, PRK, refractive surgery, retreatment

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