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Importance and management of micronutrient deficiencies in patients with Alzheimer’s disease
Authors Cardoso BR, Cominetti C, Cozzolino SMF
Received 16 November 2012
Accepted for publication 9 March 2013
Published 10 May 2013 Volume 2013:8 Pages 531—542
DOI https://doi.org/10.2147/CIA.S27983
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Bárbara Rita Cardoso,1 Cristiane Cominetti,2 Silvia Maria Franciscato Cozzolino1
1Faculty of Pharmaceutical Sciences, University of São Paulo (USP), São Paulo, Brazil; 2Faculty of Nutrition, Federal University of Goiás, Goiás, Brazil
Abstract: Alzheimer’s disease (AD) is the most common form of dementia, and it generally affects the elderly. It has been suggested that diet is an intensively modifiable lifestyle factor that might reduce the risk of AD. Because epidemiological studies generally report the potential neuronal protective effects of various micronutrients, the aim of this study was to perform a literature review on the major nutrients that are related to AD, including selenium, vitamins C and E, transition metals, vitamin D, B-complex vitamins, and omega-3 fatty acids.
Keywords: Alzheimer’s disease, nutritional deficiencies, diet, oxidative stress, lipid, vitamins
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