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Drug Design, Development and Therapy
ISSN: 1177-8881
- View all (4148)
- Volume 18, 2024 (109)
- Volume 17, 2023 (283)
- Volume 16, 2022 (316)
- Volume 15, 2021 (399)
- Volume 14, 2020 (477)
- Volume 13, 2019 (387)
- Volume 12, 2018 (382)
- Volume 11, 2017 (330)
- Volume 10, 2016 (374)
- Volume 9, 2015 (543)
- Volume 8, 2014 (231)
- Volume 7, 2013 (143)
- Volume 6, 2012 (42)
- Volume 5, 2011 (40)
- Volume 4, 2010 (35)
- Volume 3, 2009 (27)
- Volume 2, 2008 (29)
- Volume 1, 2007 (1)
Journal Articles:
- 4,148 records -
Comparative Bleeding Risk of Brand Vs Generic Rivaroxaban in Elderly Inpatients with Atrial Fibrillation
Chen G, Chen J, Zhao Q, Zhu Y
Drug Design, Development and Therapy 2024, 18:1573-1582
Published Date: 13 May 2024
A Comprehensive Update of Anti-COVID-19 Activity of Heterocyclic Compounds
Nazir MS, Ahmad M, Aslam S, Rafiq A, Al-Hussain SA, Zaki MEA
Drug Design, Development and Therapy 2024, 18:1547-1571
Published Date: 8 May 2024
A Novel Tetramethylpyrazine Chalcone Hybrid- HCTMPPK, as a Potential Anti-Lung Cancer Agent by Downregulating MELK
Ma Y, Cui Q, Zhu W, Wang M, Zhai L, Hu W, Liu D, Liu M, Li Y, Li M, Han W
Drug Design, Development and Therapy 2024, 18:1531-1546
Published Date: 7 May 2024
Impact of Opioid-Free Anesthesia on Postoperative Quality of Recovery in Patients After Laparoscopic Cholecystectomy: A Randomized Controlled Trial [Letter]
Xue B
Drug Design, Development and Therapy 2024, 18:1529-1530
Published Date: 6 May 2024
ED-71 Improves Bone Mass in Ovariectomized Rats by Inhibiting Osteoclastogenesis Through EphrinB2-EphB4-RANKL/OPG Axis
Wang K, Kou Y, Rong X, Wei L, Li J, Liu H, Li M, Song H
Drug Design, Development and Therapy 2024, 18:1515-1528
Published Date: 6 May 2024
Naodesheng Pills Ameliorate Cerebral Ischemia Reperfusion-Induced Ferroptosis via Inhibition of the ERK1/2 Signaling Pathway
Yang YY, Deng RR, Xiang DX
Drug Design, Development and Therapy 2024, 18:1499-1514
Published Date: 2 May 2024
Network Pharmacology and Molecular Docking Identify the Potential Mechanism and Therapeutic Role of Scutellaria baicalensis in Alzheimer’s Disease [Letter]
Yulion R, Andriani L, Aliyah SH
Drug Design, Development and Therapy 2024, 18:1497-1498
Published Date: 2 May 2024
Advances in Nanotechnology for Enhancing the Solubility and Bioavailability of Poorly Soluble Drugs
Liu Y, Liang Y, Yuhong J, Xin P, Han JL, Du Y, Yu X, Zhu R, Zhang M, Chen W, Ma Y
Drug Design, Development and Therapy 2024, 18:1469-1495
Published Date: 1 May 2024
Dose-Response Study of Phenylephrine for Preventing Spinal-Induced Hypotension During Cesarean Delivery with Combined Spinal-Epidural Anesthesia Under the Effect of Prophylactic Intravenous Ondansetron
Sun XX, Qian J, Fan JM, Liu L, Jin XF, Xiao F
Drug Design, Development and Therapy 2024, 18:1459-1467
Published Date: 30 April 2024
Integrated Network Pharmacology Analysis and Experimental Validation to Elucidate the Mechanism of Acteoside in Treating Diabetic Kidney Disease
Zhang SJ, Zhang YF, Bai XH, Zhou MQ, Zhang ZY, Zhang SX, Cao ZJ, Wang L, Ding SW, Zheng HJ, Liu YN, Yu GY, Liu WJ
Drug Design, Development and Therapy 2024, 18:1439-1457
Published Date: 30 April 2024
Network and Experimental Pharmacology on Mechanism of Yixintai Regulates the TMAO/PKC/NF-κB Signaling Pathway in Treating Heart Failure
Wang Z, Liu C, Wei J, Yuan H, Shi M, Zhang F, Zeng Q, Huang A, Du L, Li Y, Guo Z
Drug Design, Development and Therapy 2024, 18:1415-1438
Published Date: 30 April 2024
The Molecular Biological Mechanism of Hydrogen Therapy and Its Application in Spinal Cord Injury
Hu Q, Li Y, Lin Z, Zhang H, Chen H, Chao C, Zhao C
Drug Design, Development and Therapy 2024, 18:1399-1414
Published Date: 29 April 2024
Research Progress of Long Non-Coding RNA in Tumor Drug Resistance: A New Paradigm
Zhang J, Wu L, Wang C, Xie X, Han Y
Drug Design, Development and Therapy 2024, 18:1385-1398
Published Date: 26 April 2024
Dynasore Alleviates LPS-Induced Acute Lung Injury by Inhibiting NLRP3 Inflammasome-Mediated Pyroptosis
Shan M, Wan H, Ran L, Ye J, Xie W, Lu J, Hu X, Deng S, Zhang W, Chen M, Wang F, Guo Z
Drug Design, Development and Therapy 2024, 18:1369-1384
Published Date: 23 April 2024
Propofol and Dexmedetomidine Ameliorate Endotoxemia-Associated Encephalopathy via Inhibiting Ferroptosis
Zhou Y, Yang Y, Yi L, Pan M, Tang W, Duan H
Drug Design, Development and Therapy 2024, 18:1349-1368
Published Date: 23 April 2024
Effect of Fluid Therapy in Early Morning on the Incidence of Post-Induction Hypotension During Non-Cardiac Surgery After Noon: A Single-Center Retrospective Study
Zhang Y, Wang X, Sang X, Zhou Z, Dai G, Zhang X
Drug Design, Development and Therapy 2024, 18:1339-1347
Published Date: 22 April 2024
Validation of Core Ingredients and Molecular Mechanism of Cinobufotalin Injection Against Liver Cancer
Chen S, Li M, Xue C, Zhou X, Wei J, Zheng L, Duan Y, Deng H, Tang F, Xiong W, Xiang B, Zhou M
Drug Design, Development and Therapy 2024, 18:1321-1338
Published Date: 23 April 2024
The Median Effective Dose of Intrathecal Hyperbaric Bupivacaine for Cesarean Section at Moderately High-Altitude
Yang C, Dong W, Luo J, Ma M, Gao Y, Ni L, Liu H, Cha C, Xiao Y, Huang S
Drug Design, Development and Therapy 2024, 18:1313-1319
Published Date: 22 April 2024
Natural and Synthetic Drugs Approached for the Treatment of Recurrent Aphthous Stomatitis Over the Last Decade
Vitamia C, Iftinan GN, Latarissa IR, Wilar G, Cahyanto A, Elamin KM, Wathoni N
Drug Design, Development and Therapy 2024, 18:1297-1312
Published Date: 22 April 2024
RNA-Based Antipsoriatic Gene Therapy: An Updated Review Focusing on Evidence from Animal Models
Lin ZC, Hung CF, Aljuffali IA, Lin MH, Fang JY
Drug Design, Development and Therapy 2024, 18:1277-1296
Published Date: 23 April 2024
Obacunone Alleviates Inflammatory Pain by Promoting M2 Microglial Polarization and by Activating Nrf2/HO-1 Signaling Pathway
Nan F, Tian Q, Chen S
Drug Design, Development and Therapy 2024, 18:1265-1275
Published Date: 18 April 2024
Cinnamaldehyde Inhibits the Function of Osteosarcoma by Suppressing the Wnt/β-Catenin and PI3K/Akt Signaling Pathways [Retraction]
Huang Y, Chen J, Yang S, Tan T, Wang N, Wang Y, Zhang L, Yang C, Huang H, Luo J, Luo X
Drug Design, Development and Therapy 2024, 18:1263-1264
Published Date: 18 April 2024
Sinomenine Hydrochloride Protects IgA Nephropathy Through Regulating Cell Growth and Apoptosis of T and B Lymphocytes
Li JJ, Li L, Li S, Tang XY, Sun HF, Liu JX
Drug Design, Development and Therapy 2024, 18:1247-1262
Published Date: 17 April 2024
Dexamethasone versus Dexmedetomidine as Adjuvants in Ultrasound Popliteal Sciatic Nerve Block for Hallux Valgus Surgery: A Mono-Centric Retrospective Comparative Study
Coviello A, Iacovazzo C, Cirillo D, Bernasconi A, Marra A, Squillacioti F, Martone M, Garone E, Coppola F, de Siena AU, Vargas M, Servillo G
Drug Design, Development and Therapy 2024, 18:1231-1245
Published Date: 17 April 2024
Clinical Application and Research Progress of Remimazolam for Pediatric Patients
Bai C, Xu M, Guo Y, Jin Y, Zhao X
Drug Design, Development and Therapy 2024, 18:1221-1229
Published Date: 17 April 2024
Network Pharmacology and Molecular Docking Identify the Potential Mechanism and Therapeutic Role of Scutellaria baicalensis in Alzheimer’s Disease
Peng Y, Zhou C
Drug Design, Development and Therapy 2024, 18:1199-1219
Published Date: 17 April 2024
Effect of S-Ketamine on Postoperative Nausea and Vomiting in Patients Undergoing Video-Assisted Thoracic Surgery: A Randomized Controlled Trial
Qi Y, Zhou M, Zheng W, Dong Y, Li W, Wang L, Xu H, Zhang M, Yang D, Wang L, Zhou H
Drug Design, Development and Therapy 2024, 18:1189-1198
Published Date: 16 April 2024
A Novel Network Pharmacology Strategy Based on the Universal Effectiveness-Common Mechanism of Medical Herbs Uncovers Therapeutic Targets in Traumatic Brain Injury
Yu Z, Ding R, Yan Q, Cheng M, Li T, Zheng F, Zhu L, Wang Y, Tang T, Hu E
Drug Design, Development and Therapy 2024, 18:1175-1188
Published Date: 16 April 2024
Citric Acid Controls the Activity of YopH Bacterial Tyrosine Phosphatase
Styszko J, Kostrzewa T, Gorska-Ponikowska M, Kuban-Jankowska A
Drug Design, Development and Therapy 2024, 18:1165-1174
Published Date: 11 April 2024
Outcome of Darunavir–Cobicistat-Based Regimens in HIV-Infected People Who Have Experienced Virological Failure
Alberton F, Galli L, Lolatto R, Candela C, Gianotti N, Chiurlo M, Ranzenigo M, Strano M, Uglietti A, Castagna A
Drug Design, Development and Therapy 2024, 18:1153-1163
Published Date: 10 April 2024
The Promise of Therapeutic Psilocybin: An Evaluation of the 134 Clinical Trials, 54 Potential Indications, and 0 Marketing Approvals on ClinicalTrials.gov
Norring SA, Spigarelli MG
Drug Design, Development and Therapy 2024, 18:1143-1151
Published Date: 10 April 2024
Synthesis and Anti-Diabetic Activity of an 8-Purine Derivative as a Novel DPP-4 Inhibitor in Obese Diabetic Zücker Rats
Chayah M, Luque-González A, Gómez-Pérez V, Salagre D, Al-Shdaifat A, Campos JM, Conejo-García A, Agil A
Drug Design, Development and Therapy 2024, 18:1133-1141
Published Date: 10 April 2024
Unveiling the Mechanism of the ChaiShao Shugan Formula Against Triple-Negative Breast Cancer
Fan T, Huang Y, Liu Z, Huang J, Ke B, Rong Y, Qiu H, Zhang B
Drug Design, Development and Therapy 2024, 18:1115-1131
Published Date: 10 April 2024
Dexmedetomidine Prolongs Lidocaine Intravenous Regional Anesthesia in Rats by Blocking the Hyperpolarization-Activated Cation Current
Zhang T, Liao X, Chen Y, Shu X, Liu D, Yao Y
Drug Design, Development and Therapy 2024, 18:1103-1114
Published Date: 9 April 2024
Updated Evaluation of Agalsidase Alfa Enzyme Replacement Therapy for Patients with Fabry Disease: Insights from Real-World Data
Feriozzi S, Chimenti C, Reisin RC
Drug Design, Development and Therapy 2024, 18:1083-1101
Published Date: 3 April 2024
Mapping the Research of Ferroptosis in Parkinson’s Disease from 2013 to 2023: A Scientometric Review
Chen Y, Wu Z, Li S, Chen Q, Wang L, Qi X, Tian C, Yang M
Drug Design, Development and Therapy 2024, 18:1053-1081
Published Date: 3 April 2024
Molecular Modeling, Synthesis, and Antihyperglycemic Activity of the New Benzimidazole Derivatives – Imidazoline Receptor Agonists
Martynov A, Farber B, Bomko T, Beckles DL, Kleyn I
Drug Design, Development and Therapy 2024, 18:1035-1052
Published Date: 3 April 2024
Exploring the Median Effective Dose of Ciprofol for Anesthesia Induction in Elderly Patients: Impact of Frailty on ED50
Yuan J, Liang Z, Geoffrey MB, Xie Y, Chen S, Liu J, Xia Y, Li H, Zhao Y, Mao Y, Xing N, Yang J, Wang Z, Xing F
Drug Design, Development and Therapy 2024, 18:1025-1034
Published Date: 3 April 2024
Forsythoside B Mitigates Monocrotaline-Induced Pulmonary Arterial Hypertension via Blocking the NF-κB Signaling Pathway to Attenuate Vascular Remodeling [LETTER]
Pasiana AD, Idrus HH, Purnamasari I
Drug Design, Development and Therapy 2024, 18:1023-1024
Published Date: 2 April 2024
The Emerging Roles of Nanocarrier Drug Delivery System in Treatment of Intervertebral Disc Degeneration-Current Knowledge, Hot Spots, Challenges and Future Perspectives
Hu Y, Yang R, Liu S, Song Z, Wang H
Drug Design, Development and Therapy 2024, 18:1007-1022
Published Date: 29 March 2024
Revolutionizing Stroke Recovery: Unveiling the Promise of Stem Cell Therapy
Panos LD, Bargiotas P, Arnold M, Hadjigeorgiou G, Panos GD
Drug Design, Development and Therapy 2024, 18:991-1006
Published Date: 29 March 2024
The Potential of Exosomes for Osteoporosis Treatment: A Review
He Y, Chen Y
Drug Design, Development and Therapy 2024, 18:979-989
Published Date: 28 March 2024
The Safety and Efficacy of Remimazolam Compared to Dexmedetomidine for Awake Tracheal Intubation by Flexible Bronchoscopy: A Randomized, Double-Blind, Controlled Trial
Chen Q, Qin B, Zhang M, Zhou Y, Shi X, Xie Y
Drug Design, Development and Therapy 2024, 18:967-978
Published Date: 28 March 2024
Neurophysiological Characteristics in Type II and Type III 5q Spinal Muscular Atrophy Patients: Impact of Nusinersen Treatment
Li D, Sun N, Xiang L, Liu J, Wang X, Yang L, Huang S
Drug Design, Development and Therapy 2024, 18:953-965
Published Date: 28 March 2024
A Review of Dupilumab in the Treatment of Atopic Dermatitis in Infants and Children
Wang M, Gao XH, Zhang L
Drug Design, Development and Therapy 2024, 18:941-951
Published Date: 27 March 2024
The Impact of Baohuoside I on the Metabolism of Tofacitinib in Rats
Shi Y, Lu Z, Song W, Wang Y, Zhou Q, Geng P, Zhou Y, Wang S, Han A
Drug Design, Development and Therapy 2024, 18:931-939
Published Date: 25 March 2024
Effect of Intraoperative infusion Magnesium Sulfate Infusion on Postoperative Quality of Recovery in Patients Undergoing Total Knee Arthroplasty: A Prospective, Double-Blind, Randomized Controlled Trial
Xu H, Hao C, Wang X, Du J, Zhang T, Zhang X
Drug Design, Development and Therapy 2024, 18:919-929
Published Date: 25 March 2024
Intracranial Efficacy of Pyrotinib and Capecitabine Combination Therapy in HER2-Positive Breast Cancer with Brain Metastases
Wang C, Xiang J, Zhang Q, Li J, Liu Y, Liu J
Drug Design, Development and Therapy 2024, 18:909-917
Published Date: 23 March 2024
Harmonising IV Oxycodone with Paediatric Perioperative Medications: A Compatibility Study Through Y-Type Connectors
Youssef SH, Garg A, Song Y, Wylie NE, Garg S
Drug Design, Development and Therapy 2024, 18:899-908
Published Date: 22 March 2024
The Efficacy of Chaihu-Guizhi-Ganjiang Decoction on Chronic Non-Atrophic Gastritis with Gallbladder Heat and Spleen Cold Syndrome and Its Metabolomic Analysis: An Observational Controlled Before-After Clinical Trial
Wen T, Liu X, Pang T, Li M, Jiao G, Fan X, Tang J, Zhang C, Wang Z, Yue X, Chen W, Zhang F
Drug Design, Development and Therapy 2024, 18:881-897
Published Date: 21 March 2024