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Drug Design, Development and Therapy
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Drug Design, Development and Therapy
(151,085) Views
Editor in Chief Daniel S Pilch, PhD
1177-8881
Treatment of glioblastoma multiforme cells with temozolomide-BioShuttle ligated by the inverse Diels-Alder ligation chemistryKlaus Braun, Manfred Wiessler, Volker Ehemann, Ruediger Pipkorn, Herbert Spring, et al
Raltegravir in the management of HIV-infected patients
Hans-Jürgen Stellbrink
Ambrisentan for the treatment of pulmonary arterial hypertension
Brian Casserly, James R Klinger
Antidiabetic Bis-Maltolato-OxoVanadium(IV): Conversion of inactive trans- to bioactive cis-BMOV for possible binding to target PTP-1B
Thomas Scior, Hans-Georg Mack, José Antonio Guevara García, Wolfhard Koch
Drug design with Cdc7 kinase: a potential novel cancer therapy target
Masaaki Sawa, Hisao Masai
Once-daily transdermal rivastigmine in the treatment of Alzheimer’s disease
Andreas Wentrup, Wolfgang H Oertel, Richard Dodel
Development and targeted use of nilotinib in chronic myeloid leukemia
Carmen Fava, Hagop Kantarjian, Jorge Cortes, Elias Jabbour
Severe toxicity of skin rash, fever and diarrhea associated with imatinib: case report and review of skin toxicities associated with tyrosine kinase inhibitors
Xuan Huang, Samir Patel, Nasir Ahmed, Karen Seiter, Delong Liu
Review of pramlintide as adjunctive therapy in treatment of type 1 and type 2 diabetes
Gina Ryan, Tim A Briscoe, Lynette Jobe
Transdermal hormone therapy in postmenopausal women: A review of metabolic effects and drug delivery technologies
Nathan W Kopper, Jennifer Gudeman
Next-generation anthracycline for the management of small cell lung cancer: focus on amrubicin
Michiko Yamamoto, Akira Takakura, Noriyuki Masuda
Polyethylenimine-mediated gene delivery to the lung and therapeutic applications
Sante Di Gioia, Massimo Conese
Maraviroc in the treatment of HIV infection
Neelanjana Ray
Surface activity of surfactant spiked with vitamin A
Vadim Bronshtein, Vugranam Venkatesh, Jas Aulakh, Philippe Chessex
Submucosal injection solution for gastrointestinal tract endoscopic mucosal resection and endoscopic submucosal dissection
Toshio Uraoka, Yutaka Saito, Kazuhide Yamamoto, Takahiro Fujii
Gene medicine for cancer treatment: Commercially available medicine and accumulated clinical data in China
Guangyu Ma, Hideaki Shimada, Kenzo Hiroshima, Yuji Tada, Nobuo Suzuki, Masatoshi Tagawa
Comparative in vivo bioequivalence and in vitro dissolution of two valproic acid sustained-release formulations
Akira Fujii, Norio Yasui-Furukori, Taku Nakagami, Takenori Niioka, Manabu Saito, et al
Structure-based design of anticancer prodrug PABA/NO
Xinhua Ji, Ajai Pal, Ravi Kalathur, Xun Hu, Yijun Gu, et al
A phase I clinical study of VB4-845: Weekly intratumoral administration of an anti-EpCAM recombinant fusion protein in patients with squamous cell carcinoma of the head and neck
Glen C MacDonald, Michèle Rasamoelisolo, Joycelyn Entwistle, Jeannick Cizeau, Denis Bosc, et al
Pharmacological control of neutrophil-mediated inflammation: Strategies targeting calcium handling by activated polymorphonuclear leukocytes
Gregory R Tintinger, Helen C Steel, Annette J Theron, Ronald Anderson
Modafinil in the treatment of excessive sleepiness
Jonathan RL Schwartz
Changes in CD4+ T-cells and HIV RNA resulting from combination of anti-TB therapy with Dzherelo in TB/HIV dually infected patients
Lyudmila G Nikolaeva, Tatyana V Maystat, Lilia A Masyuk, Volodymyr S Pylypchuk, Yuri L Volyanskii, Galyna A Kutsyna
Induction of cytotoxicity, apoptosis and cell cycle arrest by 1-t-butyl carbamoyl, 7-methyl-indole-3-ethyl isothiocyanate (NB7M) in nervous system cancer cells
Laurent Brard, Rakesh K Singh, Kyu Kwang Kim, Thilo S Lange, Giselle L Saulier Sholler
Discovery, development, and clinical application of sugammadex sodium, a selective relaxant binding agent
Mark Welliver, John McDonough, Nicholas Kalynych, Robert Redfern
Aerosol delivery by an ultrasonic nebulizer during different mechanical ventilation settings in a lung model – a pilot study
Michael Winterhalter, Michael Bund, Nawid Khaladj, Christian Hagl, Andre Simon, et al
A safety-modified SV40 Tag developed for human cancer immunotherapy
Stephanie S Tseng-Rogenski, Mohamed S Arredouani, June F Escara-Wilke, Yilin C Neeley, Michael J Imperiale et al
Pharmaco-management of inhalation injuries for burn survivors
Anthony C Bartley, Dale W Edgar, Fiona M Wood
Outcome of anthroposophic medication therapy in chronic disease: A 12-month prospective cohort study
Harald J Hamre, Claudia M Witt, Anja Glockmann, Renatus Ziegler, Gunver S Kienle et al
Optimization of experimental parameters for the production of LMWH-loaded polymeric microspheres
Nusrat Motlekar, Bi-Botti Youan
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