Back to Browse Journals » Clinical Interventions in Aging » Volume 5

Assessment of cumulative exposure to UVA through study of asymmetric facial skin damage

Authors Sophie Mac-Mary1, Jean-Marie Sainthillier1, Adeline Jeudy3, et al

Published Date September 2010 Volume 2010:5 Pages 277—284


Published 6 September 2010

Sophie Mac-Mary1, Jean-Marie Sainthillier1, Adeline Jeudy3, Christelle Sladen2, Cara Williams2, Mike Bell2, Philippe Humbert3
1Skinexigence SAS, Saint-Jacques University Hospital, Besançon, France; 2The Boots Company, Nottingham, United Kingdom; 3Research and Studies Center on the Integument, Department of Dermatology, Saint-Jacques University Hospital, University of Franche-Comté, Besançon, France

Background: Published studies assessing whether asymmetric facial ultraviolet light exposure leads to underlying differences in skin physiology and morphology are only observational. The aim of this study was to assess the visual impact on the skin of repeated ultraviolet-A (UVA) exposure through a window.
Methods: Eight women and two men presenting with asymmetric signs of photoaging due to overexposure of one side of their face to the sun through a window over a long period of time were enrolled in the study. Split-face biometrologic assessments were performed (clinical scoring, hydration with Corneometer®, mechanical properties with a Cutometer®, transepidermal water loss with AquaFlux®, skin relief with fringe projection, photography, stripping, and then lipid peroxidation analyses).
Results: Significant differences were observed in clinical scores for wrinkles, skin roughness assessed by fringe projection on the cheek, and skin heterogeneity assessed with spectrocolorimetry on the cheekbone. Other differences were observed for skin hydration, as well as skin laxity, which tended towards significance.
Discussion: This study suggests the potential benefit of daily UVA protection during nondeliberate exposure indoors as well as outside.

Keywords: UVA, asymmetry, photodamage, face

Download Article [PDF] 

Creative Commons License This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution - Non Commercial (unported, v3.0) License. The full terms of the License are available at Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be found at:

Readers of this article also read:

Association between calcifying nanoparticles and placental calcification

Guo Y, Zhang D, Lu H, Luo S, Shen X

International Journal of Nanomedicine 2012, 7:1679-1686

Published Date: 27 March 2012

Radio electric asymmetric brain stimulation in the treatment of behavioral and psychiatric symptoms in Alzheimer disease

Mannu P, Rinaldi S, Fontani V, Castagna A

Clinical Interventions in Aging 2011, 6:207-211

Published Date: 26 July 2011

Bisphosphonate use and hip fracture epidemiology: ecologic proof from the contrary

Alex Fisher, Jodie Martin, Wichat Srikusalanukul, et al

Clinical Interventions in Aging 2010, 5:355-362

Published Date: 19 November 2010

Elderly quality of life impacted by traditional chinese medicine techniques

Helena A Figueira, Olivia A Figueira, Alan A Figueira, et al

Clinical Interventions in Aging 2010, 5:301-305

Published Date: 1 October 2010

Facial rejuvenation for middle-aged women: a combined approach with minimally invasive procedures

Alberto Goldman, Uwe Wollina

Clinical Interventions in Aging 2010, 5:293-299

Published Date: 14 September 2010

Assessment and management of nutrition in older people and its importance to health

Tanvir Ahmed, Nadim Haboubi

Clinical Interventions in Aging 2010, 5:207-216

Published Date: 29 July 2010

Treating glabellar lines with botulinum toxin type A-hemagglutinin complex: A review of the science, the clinical data, and patient satisfaction

Koenraad De Boulle, Steven Fagien, Boris Sommer, et al

Clinical Interventions in Aging 2010, 5:101-118

Published Date: 13 April 2010

Eggshell membrane: A possible new natural therapeutic for joint and connective tissue disorders. Results from two open-label human clinical studies

Kevin J Ruff, Dale P DeVore, Michael D Leu, Mark A Robinson

Clinical Interventions in Aging 2009, 4:235-240

Published Date: 18 May 2009