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International Journal of Women's Health

ISSN: 1179-1411


Journal Articles:

PCOS and Fertility Treatments

Polycystic ovary syndrome (PCOS) affects 6–10% of women in reproductive age and is characterized by hyperandrogenism, insulin resistance, and chronic anovulation. It is a heterogeneous syndrome with not completely understood aetiology that is related to a complex interaction between metabolic, endocrine, genetic, and environmental factors.

This is an important topic as women diagnosed with PCOS are at higher risk for type 2 diabetes, high blood pressure, obesity, and endometrial cancer. Increasing evidence suggests that insulin resistance and secondary hyperinsulinemia play a key synergistic role with hyperandrogenism in the development and maintenance of metabolic alterations and anovulation or irregular cycles in both obese and lean patients with PCOS.