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Revisiting corneal topography for the diagnosis of keratoconus: use of Rabinowitz's KISA% index
Authors Sedghipour MR, Lotfi-Sadigh A, Motlagh BF
Received 14 July 2011
Accepted for publication 23 August 2011
Published 26 January 2012 Volume 2012:6 Pages 181—184
DOI https://doi.org/10.2147/OPTH.S24219
Review by Single anonymous peer review
Peer reviewer comments 2
Mohammad Reza Sedghipour, Afshin Lotfi Sadigh, Behzad Fallahi Motlagh
Department of Ophthalmology, Tabriz University of Medical Sciences, Tabriz, Iran
Background: Numerous videokeratographic methods are used in the diagnosis of keratoconus.The purpose of this study was to compare the sensitivity and specificity of the KISA% index with the keratometry (K) value, inferior-superior (I-S) value, relative skewing of the steepest radial axes (SRAX), and keratometric astigmatism (AST) indices in 25 patients presenting with bilateral keratoconus.
Methods: Twenty-five patients presenting with bilateral keratoconus were enrolled. Fifty eyes from 25 healthy individuals without corneal abnormalities were used as controls. The clinical diagnosis of keratoconus was made by observation of scissors reflex at retinoscopy and characteristic slit lamp findings. Corneal topographic analysis was performed in each eye to calculate the K value, I-S value, AST, and SRAX indices.
Results: The keratoconus percentage index (KISA%) was significantly more sensitive and specific than the other indices examined. Furthermore, it was significantly better at predicting positive and negative results than the other indices included in the study.
Conclusion: The current research suggests that KISA% could be used to detect/diagnose keratoconus but further studies are required to confirm the specificity and sensitivity of KISA% for the detection of early-stage disease and keratoconus suspects.
Keywords: cornea, keratoconus, KISA% index
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