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International Journal of Nanomedicine
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Influence of nanophase titania topography on bacterial attachment and metabolism
Original Research
(3272) Views (671) Full article downloads
Authors: Margaret R Park, Michelle K Banks, Bruce Applegate, Thomas J Webster
Published Date December 2008
Volume 2008:3(4) Pages 497 - 504
DOI: http://dx.doi.org/10.2147/IJN.S4399
Margaret R Park1, Michelle K Banks1, Bruce Applegate2, Thomas J Webster3
1School of Civil Engineering; 2Department of Food Science; 3School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA
Abstract: Surfaces with nanophase compared to conventional (or nanometer smooth) topographies are known to have different properties of area, charge, and reactivity. Previously published research indicates that the attachment of certain bacteria (such as Pseudomonas fluorescens 5RL) is higher on surfaces with nanophase compared to conventional topographies, however, their effect on bacterial metabolism is unclear. Results presented here show that the adhesion of Pseudomonas fluorescens 5RL and Pseudomonas putida TVA8 was higher on nanophase than conventional titania. Importantly, in terms of metabolism, bacteria attached to the nanophase surfaces had higher bioluminescence rates than on the conventional surfaces under all nutrient conditions. Thus, the results from this study show greater select bacterial metabolism on nanometer than conventional topographies, critical results with strong consequences for the design of improved biosensors for bacteria detection.
Keywords: bacteria, attachment, nanophase, topography, metabolism
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Erratum
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