The Application of Clinical Genetics

Genetics Disorders in Consanguineous Populations

Consanguineous marriages, which are unions between people who are closely related, have a long history in many cultures around the world. While such weddings occur in a variety of communities worldwide, they are especially widespread in some places where cultural, societal, and religious variables impact marital traditions. Consanguinity has important consequences for population genetic health since it increases the risk of inheriting genetic diseases. This Article Collection highlights the complexities of genetic disorders in consanguineous populations and to spark discussion and action towards addressing the particular opportunities and challenges in this field.