Back to Browse Journals » Clinical Ophthalmology » Volume 4

Endophthalmitis: Pathogenesis, clinical presentation, management, and perspectives

Authors M Kernt, A Kampik

Published Date March 2010 Volume 2010:4 Pages 121—135

DOI http://dx.doi.org/10.2147/OPTH.S6461

Published 5 March 2010

M Kernt, A Kampik

Department of Ophthalmology, Ludwig Maximilian University, Munich, Germany

Abstract: Endophthalmitis is a rare but sight-threatening complication that can occur after ocular surgery or trauma or as a consequence of systemic infection. To optimize visual outcome, early diagnosis and treatment are essential. Over recent decades, advances in hygienic standards, improved microbiologic and surgical techniques, development of powerful antimicrobial drugs, and the introduction of intravitreal antibiotic therapy have led to a decreased incidence and improved management of endophthalmitis. However, endophthalmitis still represents a serious clinical problem. This review focuses on current principles and techniques for evaluation and treatment of endophthalmitis. In addition, it addresses recent developments regarding antimicrobial treatment and prophylaxis of infectious endophthalmitis.

Keywords: endophthalmitis, intravitreal, antibiotics, victrectomy, moxifloxacin, voriconazole, caspofungin

Download Article [PDF] 

Creative Commons License This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution - Non Commercial (unported, v3.0) License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be found at: http://www.dovepress.com/permissions.php

Other articles by this author:

Assessment of β-zone peripapillary atrophy by optical coherence tomography and scanning laser ophthalmoscopy imaging in glaucoma patients

Seidensticker F, Reznicek L, Mann T, Huebert I, Kampik A, Ulbig M, Hirneiss C, Neubauer AS, Kernt M

Clinical Ophthalmology 2014, 8:1233-1239

Published Date: 27 June 2014

Correlation between peripapillary retinal nerve fiber layer thickness and fundus autofluorescence in primary open-angle glaucoma

Reznicek L, Seidensticker F, Mann T, Hübert I, Buerger A, Haritoglou C, Neubauer AS, Kampik A, Hirneiss C, Kernt M

Clinical Ophthalmology 2013, 7:1883-1888

Published Date: 19 September 2013

Navigated macular laser decreases retreatment rate for diabetic macular edema: a comparison with conventional macular laser

Neubauer AS, Langer J, Liegl R, Haritoglou C, Wolf A, Kozak I, Seidensticker F, Ulbig M, Freeman WR, Kampik A, Kernt M

Clinical Ophthalmology 2013, 7:121-128

Published Date: 16 January 2013

Pain and accuracy of focal laser treatment for diabetic macular edema using a retinal navigated laser (Navilas®)

Kernt M, Cheuteu RE, Cserhati S, Seidensticker F, Liegl RG, Lang J, Haritoglou C, Kampik A, Ulbig MW, Neubauer AS

Clinical Ophthalmology 2012, 6:289-296

Published Date: 27 February 2012

Wide-field fundus autofluorescence corresponds to visual fields in chorioretinitis patients

Seidensticker F, Neubauer AS, Wasfy T, Stumpf C, Thurau SR, Kampik A, Kernt M

Clinical Ophthalmology 2011, 5:1667-1671

Published Date: 29 November 2011

Choroidal pigmented lesions imaged by ultra-wide-field scanning laser ophthalmoscopy with two laser wavelengths (Optomap)

Marcus Kernt, Ulrich C Schaller, Carmen Stumpf, et al

Clinical Ophthalmology 2010, 4:829-836

Published Date: 21 July 2010

Minocycline is cytoprotective in human trabecular meshwork cells and optic nerve head astrocytes by increasing expression of XIAP, survivin, and Bcl-2

Marcus Kernt, Aljoscha S Neubauer, Kirsten H Eibl, et al

Clinical Ophthalmology 2010, 4:591-604

Published Date: 29 June 2010

Readers of this article also read:

Green synthesis of water-soluble nontoxic polymeric nanocomposites containing silver nanoparticles

Prozorova GF, Pozdnyakov AS, Kuznetsova NP, Korzhova SA, Emel’yanov AI, Ermakova TG, Fadeeva TV, Sosedova LM

International Journal of Nanomedicine 2014, 9:1883-1889

Published Date: 16 April 2014

Pharmacokinetics and pharmacodynamics of acetylsalicylic acid after intravenous and oral administration to healthy volunteers

Nagelschmitz J, Blunck M, Kraetzschmar J, Ludwig M, Wensing G, Hohlfeld T

Clinical Pharmacology: Advances and Applications 2014, 6:51-59

Published Date: 19 March 2014

Methacrylic-based nanogels for the pH-sensitive delivery of 5-Fluorouracil in the colon

Ashwanikumar N, Kumar NA, Nair SA, Kumar GS

International Journal of Nanomedicine 2012, 7:5769-5779

Published Date: 15 November 2012

A novel preparation method for silicone oil nanoemulsions and its application for coating hair with silicone

Hu Z, Liao M, Chen Y, Cai Y, Meng L, Liu Y, Lv N, Liu Z, Yuan W

International Journal of Nanomedicine 2012, 7:5719-5724

Published Date: 12 November 2012

Cross-linked acrylic hydrogel for the controlled delivery of hydrophobic drugs in cancer therapy

Deepa G, Thulasidasan AK, Anto RJ, Pillai JJ, Kumar GS

International Journal of Nanomedicine 2012, 7:4077-4088

Published Date: 27 July 2012

Detemir as a once-daily basal insulin in type 2 diabetes

Nelson SE

Clinical Pharmacology: Advances and Applications 2011, 3:27-37

Published Date: 18 August 2011

Crystallization after intravitreal ganciclovir injection

Pitipol Choopong, Nattaporn Tesavibul, Nattawut Rodanant

Clinical Ophthalmology 2010, 4:709-711

Published Date: 14 July 2010