Complete response of a metastatic gastroesophageal adenocarcinoma on irinotecan-based chemotherapy in a dialysis patient

Case report

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Authors: J Verwimp, F Geurs, S Ponette, et al

Published Date May 2010 Volume 2010:3 Pages 61 - 64

DOI: http://dx.doi.org/10.2147/IJNRD.S7650

J Verwimp¹, F Geurs¹, S Ponette², J Ponette², J Martens³, K Bulté²

¹Department of Medical Oncology, ²Department of Gastroenterology, ³Department of Nephrology, Regionaal Ziekenhuis Sint-Maria, Ziekenhuislaan, Halle, Belgium

Abstract: We present the first case report of a complete response of metastatic gastroesophageal cancer in a chronic hemodialysis patient with irinotecan-based chemotherapy. An elderly dialysis patient presented with diffuse liver metastases by a gastroesophageal adenocarcinoma. He received combination chemotherapy with 5 fluorouracil and irinotecan. After six months of chemotherapy, liver scans show complete remission. The principles, practice, and experience of chemotherapy with irinotecan during dialysis are discussed.

Keywords: gastroesophageal cancer, irinotecan, chemotherapy, dialysis

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